Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28612853 | 0.82 | PRCP (0.37) | SLC6A2SLC6A4CYP2D6NPC1RAB9A | |
| SCHEMBL2653892 | 0.78 | SLC6A2 (0.34) | SLC6A2SLC6A4CYP2D6NPC1RAB9A | |
| SCHEMBL27754818 | 0.77 | SLC6A2 (0.33) | SLC6A2SLC6A4CYP2D6NPC1RAB9A | |
| SCHEMBL27415175 | 0.74 | HTR2A (0.39) | SLC6A2SLC6A4CYP2D6NPC1RAB9A | |
| SCHEMBL5083201 | 0.71 | SLC6A2 (0.37) | SLC6A2SLC6A4CYP2D6NPC1RAB9A | |
| SCHEMBL11419089 | 0.71 | SLC6A2 (0.37) | SLC6A2SLC6A4CYP2D6NPC1RAB9A | |
| SCHEMBL24999225 | 0.67 | MAOA (0.41) | SLC6A2SLC6A4CYP2D6NPC1RAB9A | |
| SCHEMBL3420534 | 0.67 | MAOA (0.41) | SLC6A2SLC6A4CYP2D6NPC1RAB9A | |
| SCHEMBL22731139 | 0.67 | HTR2A (0.37) | SLC6A2SLC6A4CYP2D6NPC1RAB9A | |
| SCHEMBL18536393 | 0.67 | HTR2A (0.37) | SLC6A2SLC6A4CYP2D6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |