SCHEMBL2653909

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1133428	0.84	MAPT (0.48)	KIF11MAPT
	SCHEMBL8954027	0.83	ALDH1A1 (0.48)	MAPTTSHR
	SCHEMBL16433917	0.82	KIF11 (0.52)	KIF11HEXAHEXBMAPTTSHR
	SCHEMBL1765105	0.81	KIF11 (0.55)	KIF11MAPTMAOB
	SCHEMBL2652679	0.81	KIF11 (0.42)	KIF11HEXAHEXBGABRPGABRD
	SCHEMBL28441441	0.79	ALDH1A1 (0.50)	MAPTTSHR
	SCHEMBL3902193	0.78	KIF11 (0.57)	KIF11HEXAHEXBTSHRMAPK1
	SCHEMBL3900997	0.78	KIF11 (0.57)	KIF11MAPTTSHRMAPK1MAOB
	SCHEMBL2656189	0.77	RXRA (0.43)	KIF11HEXAHEXBMAPTMAOB
	SCHEMBL2272743	0.77	MAPT (0.41)	KIF11MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.