Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26545845 | 0.86 | MAPT (0.47) | GAAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL26545970 | 0.81 | ALOX12 (0.51) | ILKGAAALDH1A1ALOX12LMNA | |
| SCHEMBL26546076 | 0.80 | PKM (0.49) | ILKGAAALDH1A1RAB9ANPC1 | |
| SCHEMBL26545988 | 0.80 | ALOX12 (0.65) | ILKGAAALDH1A1RAB9ANPC1 | |
| SCHEMBL26545984 | 0.80 | ALOX12 (0.65) | GAAALDH1A1ALOX12LMNAMAPK1 | |
| SCHEMBL26545834 | 0.77 | GAA (0.71) | GAAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16646115 | 0.77 | ALOX12 (0.67) | GAAALDH1A1SMN1; SMN2ALOX12LMNA | |
| SCHEMBL26546062 | 0.75 | ALOX12 (0.54) | ALDH1A1SMN1; SMN2ALOX12EGFRPKM | |
| SCHEMBL19346212 | 0.74 | FBP1 (0.51) | ILKGAAALDH1A1RAB9ANPC1 | |
| SCHEMBL26546033 | 0.73 | ALOX12 (0.67) | GAAALDH1A1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054936-B1 | 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES AS 12-LIPOXYGENASE INHIBITORS | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2023-10-18 | — | — | EP | disclosed |