Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 20/20 | 1.00 |
| ▸ | BPTF | Q12830 | 1/20 | 1.00 |
| ▸ | KAT2A | Q92830 | 1/20 | 1.00 |
| ▸ | SETDB1 | Q15047 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412997 | 1.00 | KAT2B (1.00) | KAT2BBPTFKAT2ASETDB1 | |
| SCHEMBL29413001 | 0.83 | KAT2B (1.00) | KAT2BBPTFKAT2ASETDB1 | |
| SCHEMBL26793287 | 0.75 | KAT2B (0.59) | KAT2BBPTFKAT2ASETDB1 | |
| SCHEMBL28438090 | 0.72 | KAT2B (1.00) | KAT2BBPTFKAT2ASETDB1 | |
| SCHEMBL28438091 | 0.72 | KAT2B (1.00) | KAT2BBPTFKAT2ASETDB1 | |
| SCHEMBL29413030 | 0.65 | BPTF (0.46) | KAT2BBPTFKAT2A | |
| SCHEMBL28435004 | 0.65 | BPTF (0.46) | KAT2BBPTFKAT2A | |
| SCHEMBL28431573 | 0.64 | NPC1 (0.52) | KAT2BBPTFKAT2A | |
| SCHEMBL29413023 | 0.59 | KAT2B (0.49) | KAT2BSETDB1 | |
| SCHEMBL24870219 | 0.57 | ACACB (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023219939-A1 | COMPOUNDS AND METHODS FOR TREATING FRIEDREICH'S ATAXIA | Design Therapeutics, Inc. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023192642-A2 | METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE | Design Therapeutics, Inc. (US) | 2023-10-05 | — | — | WO | disclosed |