SCHEMBL26548153

SCHEMBL26548153

C[Si](C)(C)c1ccc(-c2ccc(-c3ccc4cc(-c5ccc(C(F)(F)F)cc5)ccc4c3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 7/20 0.48
NR1H2 P55055 1/20 0.44
NR1H3 Q13133 1/20 0.44
SLC6A2 P23975 1/20 0.41
P2RY14 Q15391 1/20 0.41
LMNA P02545 2/20 0.41
THRB P10828 1/20 0.41
SCN5A Q14524 1/20 0.41
KDM4E B2RXH2 2/20 0.40
HPGD P15428 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
IDO1 P14902 1/20 0.40
TDO2 P48775 1/20 0.40
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
PTPN1 P18031 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548527 1.00 KIF11 (0.48) KIF11NR1H2NR1H3SLC6A2P2RY14
SCHEMBL26548148 1.00 KIF11 (0.48) KIF11NR1H2NR1H3SLC6A2P2RY14
SCHEMBL26548666 0.95 KIF11 (0.47) KIF11NR1H2NR1H3SLC6A2P2RY14
SCHEMBL26548671 0.95 KIF11 (0.47) KIF11NR1H2NR1H3SLC6A2P2RY14
SCHEMBL26549009 0.95 KIF11 (0.47) KIF11NR1H2NR1H3SLC6A2P2RY14
SCHEMBL26548160 0.89 RXRA (0.45) KIF11NR1H2NR1H3SCN5AIDO1
SCHEMBL26548546 0.89 RXRA (0.45) KIF11NR1H2NR1H3SCN5AIDO1
SCHEMBL26548166 0.89 RXRA (0.45) KIF11NR1H2NR1H3SCN5AIDO1
SCHEMBL26548146 0.86 KIF11 (0.58) KIF11SLC6A2P2RY14CA12CA9
SCHEMBL26548158 0.86 ESR1 (0.44) NR1H2NR1H3SCN5AHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 KIF11 3675/4885NR1H2 3032/4885NR1H3 2713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.