Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 7/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23846740 | 0.83 | FADS1 (0.59) | FADS1ALOX5GRM2 | |
| SCHEMBL7364886 | 0.82 | FADS1 (0.50) | FADS1CYP19A1ALOX5DDB1CRBN | |
| SCHEMBL7364885 | 0.82 | FADS1 (0.50) | FADS1CYP19A1ALOX5DDB1CRBN | |
| SCHEMBL5835616 | 0.82 | FADS1 (0.50) | FADS1CYP19A1ALOX5DDB1CRBN | |
| SCHEMBL15743971 | 0.79 | ALOX5 (0.41) | FADS1ALOX5GRM2DDB1CRBN | |
| SCHEMBL15744000 | 0.79 | FADS1 (0.41) | FADS1ALOX5GRM2 | |
| SCHEMBL10614331 | 0.79 | FADS1 (0.41) | FADS1CYP19A1GRM2DDB1CRBN | |
| SCHEMBL23728054 | 0.78 | MEN1 (0.44) | — | |
| SCHEMBL2385068 | 0.77 | CYP19A1 (0.44) | CYP19A1 | |
| SCHEMBL11430670 | 0.73 | PDE4A (0.56) | FADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | NAMPT, MC4R, SIRT1 | FADS1 295/4885CYP19A1 2895/4885ALOX5 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.