SCHEMBL26548334

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26548830	0.95	NPC1 (0.47)	NPC1RXFP1PDGFRBPDGFRATDO2
	SCHEMBL26548202	0.92	KDM4E (0.46)	NPC1RXFP1PDGFRBPDGFRACYP11B1
	SCHEMBL26548173	0.90	CYP1A2 (0.50)	NPC1RXFP1PDGFRBPDGFRAHSD17B1
	SCHEMBL26548365	0.89	TDO2 (0.43)	NPC1RXFP1PDGFRBPDGFRATDO2
	SCHEMBL26548335	0.89	KDM1A (0.45)	NPC1RXFP1TDO2IDO1PTPN1
	SCHEMBL26548351	0.89	KDM1A (0.45)	NPC1RXFP1TDO2IDO1PTPN1
	SCHEMBL26548340	0.89	TDO2 (0.43)	NPC1RXFP1PDGFRBPDGFRATDO2
	SCHEMBL26548688	0.89	CYP1A2 (0.48)	NPC1RXFP1PDGFRBPDGFRAHSD17B1
	SCHEMBL26549310	0.89	PDGFRB (0.52)	NPC1RXFP1PDGFRBPDGFRATDO2
	SCHEMBL26567752	0.87	PGR (0.42)	NPC1RXFP1PDGFRBPDGFRATDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.