SCHEMBL26548792

SCHEMBL26548792

C[Si](C)(C)c1ccc(-c2ccc3ccc(-c4ccc(-c5cccc6c5oc5ncccc56)nc4)cc3c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 3/20 0.33
PIK3C2A O00443 1/20 0.33
PIK3C2B O00750 1/20 0.33
PIK3R1 P27986 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3C3 Q8NEB9 1/20 0.33
CYP17A1 P05093 2/20 0.32
CYP11B2 P19099 2/20 0.32
GRK5 P34947 1/20 0.32
CYP19A1 P11511 1/20 0.31
CYP11B1 P15538 1/20 0.31
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548272 0.97 PIK3CA (0.34) PRKDCPIK3C2APIK3C2BPIK3R1PIK3CA
SCHEMBL26549279 0.92 GAK (0.35) PRKDCPIK3C2APIK3C2BPIK3R1PIK3CA
SCHEMBL26548952 0.89 PIK3CA (0.34) PRKDCPIK3C2APIK3C2BPIK3R1PIK3CA
SCHEMBL26548627 0.89 PIK3CA (0.34) PRKDCPIK3C2APIK3C2BPIK3R1PIK3CA
SCHEMBL26555289 0.88 PRKDC (0.34) PRKDCPIK3C2APIK3C2BPIK3R1PIK3CA
SCHEMBL26548781 0.88 TGFBR1 (0.38) PRKDCPIK3C2APIK3C2BPIK3R1PIK3CA
SCHEMBL26555253 0.88 PGR (0.35) PRKDCPIK3C2APIK3C2BPIK3R1PIK3CA
SCHEMBL26555273 0.88 GRK5 (0.33) PRKDCPIK3C2APIK3C2BPIK3R1PIK3CA
SCHEMBL26548786 0.88 TOP1 (0.38) PRKDCPIK3C2APIK3C2BPIK3R1PIK3CA
SCHEMBL26551848 0.87 SYK (0.35) PRKDCPIK3C2APIK3C2BPIK3R1PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 PRKDC 2422/4885PIK3C2A 4541/4885PIK3C2B 4558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.