SCHEMBL26548844

SCHEMBL26548844

FC(F)(F)c1ccc(-c2ccc3ccc(-c4ccc(-c5ccc(C(F)(F)F)cc5)nc4)cc3c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.48
MAOB P27338 1/20 0.48
IDO1 P14902 1/20 0.45
TDO2 P48775 1/20 0.45
KIF11 P52732 5/20 0.43
TOP1 P11387 2/20 0.41
NPBWR1 P48145 1/20 0.40
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
ALOX5AP P20292 2/20 0.39
FEN1 P39748 2/20 0.39
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
PPARA Q07869 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548354 0.95 KDM1A (0.49) KDM1AMAOBIDO1TDO2KIF11
SCHEMBL26548833 0.94 KDM1A (0.44) KDM1AMAOBIDO1TDO2KIF11
SCHEMBL26548843 0.94 KDM1A (0.44) KDM1AMAOBIDO1TDO2KIF11
SCHEMBL26548717 0.94 KIF11 (0.54) KDM1AMAOBIDO1TDO2KIF11
SCHEMBL26555867 0.93 KDM1A (0.43) KDM1AMAOBIDO1TDO2KIF11
SCHEMBL26567760 0.93 KDM1A (0.43) KDM1AMAOBIDO1TDO2KIF11
SCHEMBL26567798 0.93 IDO1 (0.43) KDM1AMAOBIDO1TDO2KIF11
SCHEMBL26548858 0.92 KDM1A (0.47) KDM1AMAOBIDO1TDO2KIF11
SCHEMBL26548847 0.92 TDO2 (0.45) KDM1AMAOBIDO1TDO2KIF11
SCHEMBL26548845 0.92 TDO2 (0.45) KDM1AMAOBIDO1TDO2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 KDM1A 114/4885MAOB 282/4885IDO1 2053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.