SCHEMBL26549205

SCHEMBL26549205

FC(F)(F)c1cc(-c2ccc3cc(-c4ccc(-c5cccc6ccccc56)nc4)cnc3c2)cc(C(F)(F)F)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTOR P42345 2/20 0.38
TDP1 Q9NUW8 2/20 0.37
PARP1 P09874 1/20 0.36
HSP90AA1 P07900 1/20 0.36
BIRC5 O15392 1/20 0.36
PIK3CD O00329 2/20 0.36
PIK3CA P42336 2/20 0.36
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2B Q13224 1/20 0.35
CYP2A6 P11509 1/20 0.34
MET P08581 1/20 0.34
PIK3CB P42338 1/20 0.34
PIK3CG P48736 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
CCNT1 O60563 1/20 0.34
CCNA2 P20248 1/20 0.34
CDK2 P24941 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26549200 0.92 PDGFRB (0.39) MTORHSP90AA1BIRC5PIK3CDPIK3CA
SCHEMBL26548184 0.92 TDP1 (0.40) TDP1PARP1CA12CA9CYP11B1
SCHEMBL26548699 0.91 TDP1 (0.40) TDP1PARP1CA12CA9CYP11B1
SCHEMBL26549051 0.90 MTOR (0.40) MTORTDP1PARP1HSP90AA1BIRC5
SCHEMBL26549341 0.90 MTOR (0.40) MTORTDP1PARP1HSP90AA1BIRC5
SCHEMBL26549195 0.85 PIK3CD (0.39) MTORTDP1PARP1BIRC5PIK3CD
SCHEMBL26549239 0.85 PIK3CD (0.45) MTORTDP1PARP1BIRC5PIK3CD
SCHEMBL26549247 0.85 TOP1 (0.41) PARP1GRIN1GRIN2BCYP2A6
SCHEMBL26549197 0.84 PDGFRB (0.42) MTORBIRC5PIK3CDPIK3CACA12
SCHEMBL26548182 0.84 TRPV1 (0.41) CYP11B1CYP11B2CCNT1CCNA2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 MTOR 3806/4885TDP1 924/4885PARP1 3364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.