SCHEMBL26548699

SCHEMBL26548699

FC(F)(F)c1cc(-c2ccc3ccc(-c4ccc(-c5cccc6ccccc56)nc4)cc3c2)cc(C(F)(F)F)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.40
PIM1 P11309 1/20 0.37
CYP11B1 P15538 3/20 0.37
CYP11B2 P19099 3/20 0.37
PARP1 P09874 1/20 0.37
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
HPGD P15428 1/20 0.36
TRPV1 Q8NER1 1/20 0.35
KDM1A O60341 1/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
CYP1A1 P04798 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP1B1 Q16678 1/20 0.34
IDO1 P14902 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548184 0.96 TDP1 (0.40) TDP1PIM1CYP11B1CYP11B2PARP1
SCHEMBL26548696 0.92 TRPV1 (0.40) PIM1CYP11B1CYP11B2HPGDTRPV1
SCHEMBL26549205 0.91 MTOR (0.38) TDP1CYP11B1CYP11B2PARP1CA12
SCHEMBL26567207 0.90 CYP11B1 (0.36) TDP1PIM1CYP11B1CYP11B2PARP1
SCHEMBL26548182 0.88 TRPV1 (0.41) PIM1CYP11B1CYP11B2HPGDTRPV1
SCHEMBL26548692 0.85 KDM1A (0.42) TDP1CYP11B1CYP11B2PARP1HPGD
SCHEMBL26548179 0.83 CYP11B1 (0.43) TDP1CYP11B1CYP11B2PARP1HPGD
SCHEMBL26548570 0.83 CA12 (0.45) PIM1CA12CA9CYP1A1CYP1A2
SCHEMBL26548881 0.83 CA12 (0.45) PIM1CA12CA9CYP1A1CYP1A2
SCHEMBL26548862 0.82 KDM1A (0.49) TDP1PARP1KDM1AIDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 TDP1 924/4885PIM1 1158/4885CYP11B1 1676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.