SCHEMBL26549508

SCHEMBL26549508

Clc1ccc(-c2ccc3oc4ncccc4c3c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
KDR P35968 2/20 0.40
IGF1R P08069 2/20 0.40
EGFR P00533 1/20 0.40
FLT4 P35916 1/20 0.40
TNKS O95271 1/20 0.40
GSK3B P49841 2/20 0.38
AHR P35869 3/20 0.37
NPC1 O15118 2/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36
LMNA P02545 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
PLA2G2A P14555 1/20 0.35
PLA2G4A P47712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15835993 0.89 KDM4E (0.53) ALDH1A1KDM4EKDRIGF1REGFR
SCHEMBL15836007 0.89 KDM4E (0.53) ALDH1A1KDM4EKDRIGF1REGFR
SCHEMBL15695163 0.88 KDM4E (0.53) ALDH1A1KDM4EKDRIGF1REGFR
SCHEMBL3666822 0.87 ALDH1A1 (0.51) ALDH1A1KDM4EKDRIGF1REGFR
SCHEMBL21568385 0.87 KDM4E (0.51) ALDH1A1KDM4EKDRIGF1REGFR
SCHEMBL15624398 0.86 KDM4E (0.50) ALDH1A1KDM4EGSK3BNPC1MAPT
SCHEMBL15855344 0.86 KDM4E (0.50) ALDH1A1KDM4EGSK3BNPC1MAPT
SCHEMBL22373666 0.85 ALDH1A1 (0.46) ALDH1A1KDM4EKDRTNKSGSK3B
SCHEMBL26562074 0.85 KDM4E (0.46) ALDH1A1KDM4EEGFRNPC1MAPT
SCHEMBL15855385 0.84 KDM4E (0.49) ALDH1A1KDM4EGSK3BNPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 ALDH1A1 77/4885KDM4E 884/4885KDR 4565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.