SCHEMBL3666822

SCHEMBL3666822

Clc1ccc2oc3ncccc3c2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
KDM4E B2RXH2 2/20 0.51
AHR P35869 7/20 0.49
LMNA P02545 1/20 0.46
KMT2A Q03164 1/20 0.46
GPR55 Q9Y2T6 1/20 0.46
IGF1R P08069 4/20 0.41
NPC1 O15118 2/20 0.41
TP53 P04637 1/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
EGFR P00533 2/20 0.41
FLT4 P35916 1/20 0.41
KDR P35968 1/20 0.41
NR4A2 P43354 1/20 0.41
CDC7 O00311 1/20 0.40
DYRK3 O43781 1/20 0.40
PIM1 P11309 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26549508 0.87 ALDH1A1 (0.46) ALDH1A1KDM4EAHRLMNAKMT2A
SCHEMBL24056386 0.86 AHR (0.58) ALDH1A1KDM4EAHRLMNAKMT2A
SCHEMBL25500488 0.84 NR4A2 (0.44) ALDH1A1KDM4EAHRLMNAKMT2A
SCHEMBL24911400 0.83 NR4A2 (0.42) ALDH1A1KDM4EAHRIGF1RNPC1
SCHEMBL24911592 0.83 NR4A2 (0.42) ALDH1A1KDM4EAHRIGF1RNPC1
SCHEMBL15836007 0.81 KDM4E (0.53) ALDH1A1KDM4EAHRKMT2AIGF1R
SCHEMBL15835993 0.81 KDM4E (0.53) ALDH1A1KDM4EAHRKMT2AIGF1R
SCHEMBL18015444 0.79 KDM4E (0.51) ALDH1A1KDM4EKMT2ANPC1TP53
SCHEMBL20172259 0.79 NPC1 (0.58) ALDH1A1KDM4EKMT2AIGF1RNPC1
SCHEMBL22138626 0.79 KDM4E (0.51) ALDH1A1KDM4ELMNAKMT2AIGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090076268-A1 Facile assembly of fused benzofuro-heterocycles JANSSEN PHARMACEUTICA N.V. (BE) 2009-03-19 US claimed
WO-2009035668-A1 FACILE ASSEMBLY OF FUSED BENZOFURO-HETEROCYCLES JANSSEN PHARMACEUTICA N.V. (BE) 2009-03-19 WO claimed
WO-2023085860-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-05-19 WO disclosed
US-20230157159-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-05-18 US disclosed
US-20230157159-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-05-18 US disclosed
WO-2021235906-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2021-11-25 WO disclosed
EP-3318566-B1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2020-06-24 EP disclosed
WO-2019216575-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 서울대학교산학협력단 (KR) 2019-11-14 WO disclosed
US-20190248804-A1 SPECIFICALLY SUBSTITUTED AZA-DIBENZOFURANS AND AZA-DIBENZOTHIOPHENES FOR ORGANIC ELECTRONIC DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2019-08-15 US disclosed
US-20190131547-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2019-05-02 US disclosed
US-10249827-B2 Azadibenzofurans for electronic applications UDC IRELAND LIMITED (IE) 2019-04-02 US disclosed
US-8221905-B2 Carbazole-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2012-07-17 US disclosed
EP-2240446-A2 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2010-10-20 EP disclosed
WO-2009086028-A2 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-09 WO disclosed
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-06-18 US disclosed
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-05-28 US disclosed
US-20090076268-A1 Facile assembly of fused benzofuro-heterocycles JANSSEN PHARMACEUTICA N.V. (BE) 2009-03-19 US disclosed
US-20090076268-A1 Facile assembly of fused benzofuro-heterocycles JANSSEN PHARMACEUTICA N.V. (BE) 2009-03-19 US disclosed
US-20090076268-A1 Facile assembly of fused benzofuro-heterocycles JANSSEN PHARMACEUTICA N.V. (BE) 2009-03-19 US disclosed
WO-2009035668-A1 FACILE ASSEMBLY OF FUSED BENZOFURO-HETEROCYCLES JANSSEN PHARMACEUTICA N.V. (BE) 2009-03-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190248804-A1 SPECIFICALLY SUBSTITUTED AZA-DIBENZOFURANS AND AZA-DIBENZOTHIOPHENES FOR ORGANIC ELECTRONIC DEVICES CDY1; CDY1B, CDYL, CBX8 ALDH1A1 1323/4885KDM4E 212/4885AHR 1600/4885
US-20190131547-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS AZI2, BRPF1, CCNB1 ALDH1A1 547/4885KDM4E 1361/4885AHR 3260/4885
US-20090076268-A1 Facile assembly of fused benzofuro-heterocycles BICRA, DDC, DDT ALDH1A1 739/4885KDM4E 1620/4885AHR 58/4885
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES OXA1L, PAICS, ORC3 ALDH1A1 1670/4885KDM4E 3635/4885AHR 2959/4885
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES PAICS, CYBA, OXA1L ALDH1A1 1670/4885KDM4E 3607/4885AHR 2642/4885
US-20230157159-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME NR0B1, AHR, ARL1 ALDH1A1 628/4885KDM4E 2899/4885AHR 2/4885
US-10249827-B2 Azadibenzofurans for electronic applications AZI2, BRPF1, CCNB1 ALDH1A1 547/4885KDM4E 1361/4885AHR 3260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.