Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 2/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21621161 | 0.85 | AOC1 (0.49) | AOC1AOC3SMN1; SMN2LMNAPTGS1 | |
| SCHEMBL4483021 | 0.79 | AOC1 (0.48) | AOC1AOC3SMN1; SMN2LMNAPTGS1 | |
| SCHEMBL14995307 | 0.77 | CA12 (0.49) | AOC1AOC3SMN1; SMN2LMNAPTGS1 | |
| SCHEMBL19766580 | 0.75 | AOC1 (0.58) | AOC1AOC3LMNAPTGS1MAPT | |
| SCHEMBL18934401 | 0.73 | AOC1 (0.56) | AOC1AOC3SMN1; SMN2PTGS1MAPT | |
| SCHEMBL9274896 | 0.73 | L3MBTL1 (0.38) | PTGS1CA12CA1CA2CA9 | |
| SCHEMBL1644887 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL6120121 | 0.71 | PTGS1 (0.69) | PTGS1CA12CA1CA2CA9 | |
| SCHEMBL21540857 | 0.71 | AOC1 (0.53) | AOC1AOC3LMNAPTGS1PTGS2 | |
| SCHEMBL10216217 | 0.71 | CA1 (0.46) | SMN1; SMN2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196975-A1 | COMPOUNDS THAT INTERACT WITH RAS SUPERFAMILY PROTEINS FOR TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | SHY THERAPEUTICS, LLC (US) | 2023-10-12 | — | — | WO | disclosed |