Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | RARA | P10276 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25401552 | 0.99 | SPHK1 (0.56) | THRATHRBL3MBTL1PLK1HTR2A | |
| SCHEMBL26553937 | 0.93 | L3MBTL1 (0.60) | THRATHRBL3MBTL1PLK1HTR2A | |
| Hydrochloric Acid SCHEMBL25401659 | 0.92 | L3MBTL1 (0.58) | THRATHRBL3MBTL1PLK1HTR2A | |
| SCHEMBL28562555 | 0.91 | THRA (0.64) | THRATHRBL3MBTL1PLK1NAAA | |
| SCHEMBL9491031 | 0.89 | L3MBTL1 (0.71) | THRATHRBL3MBTL1PLK1NAAA | |
| SCHEMBL15174013 | 0.87 | THRA (0.59) | THRATHRBL3MBTL1PLK1NAAA | |
| SCHEMBL9784422 | 0.86 | L3MBTL1 (0.71) | THRATHRBL3MBTL1PLK1NAAA | |
| SCHEMBL28610658 | 0.85 | THRA (0.61) | THRATHRBL3MBTL1PLK1NAAA | |
| SCHEMBL25399784 | 0.85 | L3MBTL1 (0.61) | THRATHRBL3MBTL1PLK1NAAA | |
| SCHEMBL27284919 | 0.85 | L3MBTL1 (0.61) | THRATHRBL3MBTL1PLK1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331683-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331683-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | SPNS2, SPCS2, SMN1; SMN2 | THRA 4682/4885THRB 2758/4885L3MBTL1 4246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.