Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | NAAA | Q02083 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | THRA | P10827 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | MLYCD | O95822 | 1/20 | 0.55 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.54 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25401659 | 0.99 | L3MBTL1 (0.58) | L3MBTL1NAAACA2THRATHRB | |
| SCHEMBL26553938 | 0.93 | THRA (0.57) | L3MBTL1NAAACA2THRATHRB | |
| Hydrochloric Acid SCHEMBL25401552 | 0.91 | SPHK1 (0.56) | L3MBTL1NAAACA2THRATHRB | |
| SCHEMBL9491031 | 0.91 | L3MBTL1 (0.71) | L3MBTL1NAAACA2THRATHRB | |
| SCHEMBL28562555 | 0.90 | THRA (0.64) | L3MBTL1NAAATHRATHRBPLK1 | |
| SCHEMBL9784422 | 0.88 | L3MBTL1 (0.71) | L3MBTL1NAAACA2THRATHRB | |
| SCHEMBL27284919 | 0.87 | L3MBTL1 (0.61) | L3MBTL1NAAACA2THRATHRB | |
| SCHEMBL13589447 | 0.87 | L3MBTL1 (0.56) | L3MBTL1NAAACA2PLK1MLYCD | |
| SCHEMBL25399434 | 0.86 | L3MBTL1 (0.64) | L3MBTL1NAAATHRATHRBPLK1 | |
| SCHEMBL5255837 | 0.86 | L3MBTL1 (0.64) | L3MBTL1NAAACA2THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331683-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331683-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | SPNS2, SPCS2, SMN1; SMN2 | L3MBTL1 4246/4885NAAA 4779/4885CA2 2655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.