Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | AHCY | P23526 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26554410 | 0.91 | ACHE (0.53) | ACHEAHCYADORA3ADORA2BADORA1 | |
| SCHEMBL26554412 | 0.82 | CYP2C19 (0.53) | ADORA3ADORA2BADORA1NT5EALDH1A1 | |
| SCHEMBL26554254 | 0.81 | AHCY (0.72) | AHCYADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL26554421 | 0.81 | NT5E (0.50) | ADORA3ADORA2BADORA1HSP90B1NT5E | |
| SCHEMBL19843971 | 0.78 | LMNA (0.57) | ACHEADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL6364030 | 0.76 | LMNA (0.60) | ADORA3ADORA2BADORA1NT5ELMNA | |
| SCHEMBL5415436 | 0.76 | LMNA (0.60) | ACHEADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL19837869 | 0.76 | LMNA (0.60) | ACHEADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL19843972 | 0.74 | LMNA (0.60) | ACHEADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL6363586 | 0.74 | LMNA (0.76) | ACHEADORA3NT5EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365970-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | ALIGOS THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230332153-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365970-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | NSUN2, SNRPA, SNRPF | ACHE 4837/4885AHCY 3101/4885ADORA3 1358/4885 |
| US-20230332153-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | NSUN2, SNRPA, SNRPF | ACHE 4837/4885AHCY 3101/4885ADORA3 1358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.