Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26557033 | 0.87 | GBA1 (0.43) | GBA1TLR7MAPTCCNE2CCNE1 | |
| SCHEMBL26559177 | 0.85 | GBA1 (0.46) | GBA1TLR7MAPTCCNE2CCNE1 | |
| SCHEMBL26552819 | 0.84 | GBA1 (0.59) | GBA1MAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL21456834 | 0.84 | NPY5R (0.44) | GBA1TLR7MAPTCCNE2CCNE1 | |
| SCHEMBL26551931 | 0.81 | KDM4E (0.59) | GBA1MAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL26550810 | 0.81 | TSHR (0.60) | GBA1MAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL4085042 | 0.77 | KMT2A (0.61) | TLR7MAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL4095705 | 0.75 | KMT2A (0.64) | TLR7MAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL26563939 | 0.71 | PRKDC (0.48) | TP53HTTPRKDC | |
| SCHEMBL21456820 | 0.71 | NPY5R (0.48) | GBA1TLR7MAPTCCNE2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551188-B1 | SUBSTITUTED QUINAZOLINE SULFONAMIDES AS THIOREDOXIN INTERACTING PROTEIN (TXNIP) INHIBITORS | SOUTHERN RES INST (US) | 2023-10-18 | — | — | EP | disclosed |