Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26556917 | 0.87 | GBA1 (0.44) | GBA1TLR7MAPTCCNE2CCNE1 | |
| SCHEMBL26559177 | 0.84 | GBA1 (0.46) | GBA1TLR7MAPTCCNE2CCNE1 | |
| SCHEMBL21456820 | 0.84 | NPY5R (0.48) | GBA1TLR7MAPTCCNE2CCNE1 | |
| SCHEMBL26552819 | 0.83 | GBA1 (0.59) | GBA1MAPTLMNAKMT2AHTT | |
| SCHEMBL25557265 | 0.83 | ENPP1 (0.45) | GBA1TLR7MAPTCCNE2CCNE1 | |
| SCHEMBL26550810 | 0.80 | TSHR (0.60) | GBA1MAPTLMNAKMT2AHPGD | |
| SCHEMBL26551931 | 0.80 | KDM4E (0.59) | GBA1MAPTLMNAKMT2AHPGD | |
| SCHEMBL25244953 | 0.72 | KDM4E (0.62) | TLR7MAPTLMNAKMT2AHPGD | |
| SCHEMBL21456834 | 0.71 | NPY5R (0.44) | GBA1TLR7MAPTCCNE2CCNE1 | |
| SCHEMBL26563939 | 0.70 | PRKDC (0.48) | HTTCYP1A2CYP2D6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551188-B1 | SUBSTITUTED QUINAZOLINE SULFONAMIDES AS THIOREDOXIN INTERACTING PROTEIN (TXNIP) INHIBITORS | SOUTHERN RES INST (US) | 2023-10-18 | — | — | EP | disclosed |