Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26242360 | 0.88 | CYP2C9 (0.40) | CYP2C9CYP2C19ALDH1A1CYP3A4MAPT | |
| SCHEMBL26558457 | 0.88 | CYP2C9 (0.40) | CYP2C9CYP2C19ALDH1A1CYP3A4MAPT | |
| SCHEMBL26557795 | 0.88 | CYP2C9 (0.40) | CYP2C9CYP2C19ALDH1A1CYP3A4MAPT | |
| SCHEMBL26242260 | 0.81 | ALDH1A1 (0.38) | CYP2C9CYP2C19ALDH1A1CYP3A4MAPT | |
| SCHEMBL26565772 | 0.80 | CYP2C19 (0.41) | CYP2C9CYP2C19ALDH1A1CYP3A4MAPT | |
| SCHEMBL26037726 | 0.79 | LGALS8 (0.43) | ALDH1A1CYP3A4TSHRLGALS8TDP1 | |
| SCHEMBL26037732 | 0.79 | LGALS8 (0.43) | ALDH1A1CYP3A4TSHRLGALS8TDP1 | |
| SCHEMBL26566231 | 0.79 | CYP2C19 (0.40) | CYP2C9CYP2C19ALDH1A1CYP3A4MAPT | |
| SCHEMBL26566191 | 0.79 | CYP2C19 (0.40) | CYP2C9CYP2C19ALDH1A1CYP3A4MAPT | |
| SCHEMBL24371811 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | NUDT1, PNP, ATIC | CYP2C9 906/4885CYP2C19 1262/4885ALDH1A1 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.