Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26558168 | 1.00 | TSHR (0.42) | TSHRALDH1A1CYP3A4MAPK1L3MBTL1 | |
| SCHEMBL26557776 | 0.91 | ALDH1A1 (0.38) | ALDH1A1CYP3A4MAPK1L3MBTL1TDP1 | |
| SCHEMBL26558697 | 0.89 | ALDH1A1 (0.36) | TSHRALDH1A1CYP3A4MAPK1NAAA | |
| SCHEMBL26558133 | 0.86 | NAAA (0.38) | TSHRALDH1A1CYP3A4MAPK1NAAA | |
| SCHEMBL26558150 | 0.86 | NAAA (0.38) | TSHRALDH1A1CYP3A4MAPK1NAAA | |
| SCHEMBL26558100 | 0.82 | ALDH1A1 (0.36) | ALDH1A1NAAA | |
| SCHEMBL26558101 | 0.81 | NAAA (0.36) | TSHRALDH1A1CYP3A4MAPK1L3MBTL1 | |
| SCHEMBL26558184 | 0.81 | ALDH1A1 (0.32) | TSHRALDH1A1CYP3A4LMNAMAPT | |
| SCHEMBL26558167 | 0.81 | ALDH1A1 (0.32) | TSHRALDH1A1CYP3A4LMNAMAPT | |
| SCHEMBL26558110 | 0.81 | ALDH1A1 (0.37) | TSHRALDH1A1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | NUDT1, PNP, ATIC | TSHR 3475/4885ALDH1A1 946/4885CYP3A4 1370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.