SCHEMBL26558194

SCHEMBL26558194

CCN(CC(=O)O)c1ccc(C(C)=O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.61
KMT2A Q03164 4/20 0.61
MEN1 O00255 3/20 0.61
NOX1 Q9Y5S8 3/20 0.61
MCL1 Q07820 2/20 0.61
POLB P06746 2/20 0.61
GAA P10253 2/20 0.61
ALDH1A1 P00352 5/20 0.47
TSHR P16473 3/20 0.47
MAPK1 P28482 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
USP2 O75604 1/20 0.47
TP53 P04637 1/20 0.47
PKM P14618 1/20 0.47
HSP90AA1 P07900 2/20 0.46
NSD2 O96028 1/20 0.46
G6PD P11413 1/20 0.46
CDK5 Q00535 1/20 0.46
CDK5R1 Q15078 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18360379 0.91 MAPT (0.53) MAPTKMT2AMEN1NOX1MCL1
SCHEMBL12106085 0.89 MEN1 (0.52) MAPTKMT2AMEN1NOX1MCL1
SCHEMBL10907589 0.87 ALDH1A1 (0.48) MAPTKMT2AMEN1NOX1MCL1
SCHEMBL4127840 0.87 ALDH1A1 (0.47) MAPTKMT2AMEN1NOX1MCL1
SCHEMBL181431 0.87 MAPT (0.77) MAPTKMT2AMEN1NOX1MCL1
SCHEMBL3349361 0.81 KEAP1 (0.51) MAPTKMT2AMEN1NOX1ALDH1A1
SCHEMBL8483627 0.81 ESRRG (0.48) MAPTKMT2AMEN1NOX1POLB
SCHEMBL8373779 0.81 MAPT (0.50) MAPTKMT2AMEN1NOX1MCL1
SCHEMBL1132513 0.81 ALDH1A1 (0.53) MAPTKMT2AMEN1NOX1GAA
SCHEMBL13603864 0.80 MAPT (0.48) MAPTKMT2AMEN1NOX1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230333477-A1 METHOD OF MANUFACTURING A SEMICONDUCTOR DEVICE TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2023-10-19 US disclosed