Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26558697 | 0.88 | ALDH1A1 (0.36) | ALDH1A1CYP3A4MAPTCYP2C19TSHR | |
| SCHEMBL26558434 | 0.85 | CYP2C19 (0.39) | ALDH1A1CYP3A4MAPTCYP2C19TSHR | |
| SCHEMBL26558184 | 0.80 | ALDH1A1 (0.32) | ALDH1A1CYP3A4MAPTCYP2C19TSHR | |
| SCHEMBL26558167 | 0.80 | ALDH1A1 (0.32) | ALDH1A1CYP3A4MAPTCYP2C19TSHR | |
| SCHEMBL26558170 | 0.79 | TSHR (0.35) | ALDH1A1CYP3A4TSHRLMNANAAA | |
| SCHEMBL26557816 | 0.79 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL26558155 | 0.78 | TSHR (0.34) | ALDH1A1TSHRLMNANAAAPRKCA | |
| SCHEMBL26558449 | 0.78 | ALDH1A1 (0.38) | ALDH1A1CYP3A4MAPTCYP2C19TSHR | |
| SCHEMBL26558699 | 0.78 | FAAH (0.38) | ALDH1A1CYP3A4MAPTCYP2C19TSHR | |
| SCHEMBL26558172 | 0.77 | TSHR (0.36) | ALDH1A1CYP3A4TSHRLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | NUDT1, PNP, ATIC | ALDH1A1 946/4885CYP3A4 1370/4885MAPT 3657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.