Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | IL18 | Q14116 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718154 | 0.89 | EGLN1 (0.64) | KDM4EGAAEGLN1EPHX2XDH | |
| SCHEMBL8947296 | 0.82 | MMP1 (0.68) | KDM4EGAAMEN1KMT2APOLB | |
| SCHEMBL26561269 | 0.82 | MMP13 (0.66) | KDM4EGAAMEN1KMT2ARAB9A | |
| SCHEMBL9269300 | 0.82 | RAB9A (0.48) | KDM4EEGLN1EPHX2MEN1KMT2A | |
| SCHEMBL29035428 | 0.81 | SMN1; SMN2 (0.64) | KDM4EGAAMEN1KMT2ARAB9A | |
| SCHEMBL5830902 | 0.81 | PARP15 (0.55) | PARP15PARP10PARP2KDM4EEPHX2 | |
| SCHEMBL25365642 | 0.80 | MAPK14 (0.61) | KDM4EGAAMEN1KMT2ARAB9A | |
| SCHEMBL8947242 | 0.80 | KMT2A (0.67) | KDM4EGAAXDHMEN1KMT2A | |
| SCHEMBL29523717 | 0.79 | KDM4E (0.50) | KDM4EGAAEPHX2MEN1KMT2A | |
| SCHEMBL26564743 | 0.79 | SMN1; SMN2 (0.59) | KDM4EGAAMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |