SCHEMBL26565189

SCHEMBL26565189

Pc1ccc(-c2ccc3cc(-c4ccc(-c5cccc6c5oc5ncccc56)nc4)ccc3c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.36
PRKDC P78527 4/20 0.34
PIK3CA P42336 4/20 0.34
PIK3C2A O00443 2/20 0.34
PIK3C2B O00750 2/20 0.34
PIK3R1 P27986 2/20 0.34
PIK3C3 Q8NEB9 2/20 0.34
CYP19A1 P11511 4/20 0.33
GRK5 P34947 1/20 0.33
CYP11B1 P15538 4/20 0.32
CYP11B2 P19099 4/20 0.32
CYP17A1 P05093 1/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
ABL1 P00519 2/20 0.30
PIK3CD O00329 1/20 0.30
CHUK O15111 1/20 0.30
DAPK3 O43293 1/20 0.30
PIK3C2G O75747 1/20 0.30
RAF1 P04049 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26555253 0.97 PGR (0.35) PGRPRKDCPIK3CAPIK3C2APIK3C2B
SCHEMBL26548263 0.89 L3MBTL1 (0.39) PGRPRKDCPIK3CAPIK3C2APIK3C2B
SCHEMBL26551859 0.89 PRKDC (0.34) PGRPRKDCPIK3CAPIK3C2APIK3C2B
SCHEMBL26551848 0.89 SYK (0.35) PRKDCPIK3CAPIK3C2APIK3C2BPIK3R1
SCHEMBL26551071 0.88 PIK3CA (0.35) PGRPRKDCPIK3CAPIK3C2APIK3C2B
SCHEMBL26548272 0.88 PIK3CA (0.34) PGRPRKDCPIK3CAPIK3C2APIK3C2B
SCHEMBL26548268 0.86 TOP1 (0.39) PRKDCPIK3CAPIK3C2APIK3C2BPIK3R1
SCHEMBL26565209 0.86 GRK5 (0.35) PRKDCPIK3CAPIK3C2APIK3C2BPIK3R1
SCHEMBL26551852 0.86 CYP11B1 (0.35) PRKDCPIK3CAPIK3C2APIK3C2BPIK3R1
SCHEMBL26565228 0.86 PRKDC (0.33) PRKDCPIK3CAPIK3C2APIK3C2BPIK3R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 PGR 4012/4885PRKDC 2422/4885PIK3CA 4826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.