Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE1A | P54750 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9108639 | 0.73 | CA2 (0.54) | CA2CA4TDP1MAPTPDE5A | |
| SCHEMBL10130850 | 0.69 | CA2 (0.50) | CA2CA4TDP1MAPTPDE5A | |
| SCHEMBL20226611 | 0.65 | MAPT (0.30) | MAPT | |
| SCHEMBL9766027 | 0.65 | CA2 (0.46) | CA2CA4MAPTPDE5APDE4A | |
| SCHEMBL9549629 | 0.65 | CA2 (0.46) | CA2CA4MAPT | |
| SCHEMBL357480 | 0.65 | CA2 (0.46) | CA2CA4MAPTPDE5APDE4A | |
| SCHEMBL7971157 | 0.65 | CA2 (0.46) | CA2CA4MAPTPDE5APDE4A | |
| SCHEMBL6439100 | 0.65 | CA2 (0.46) | CA2CA4MAPTPDE5APDE4A | |
| SCHEMBL9962327 | 0.65 | CA2 (0.46) | CA2CA4MAPTPDE5APDE4A | |
| SCHEMBL15961197 | 0.63 | CA2 (1.00) | CA2CA4MAPTCA1CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331676-A1 | NAPHTHYLUREA COMPOUND, METHODS OF PREPARATION AND USE THEREOF | HENAN RADIOMEDICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331676-A1 | NAPHTHYLUREA COMPOUND, METHODS OF PREPARATION AND USE THEREOF | NPM1, NCL, NOC2L | CA2 3089/4885CA4 2295/4885TDP1 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.