SCHEMBL10130850

SCHEMBL10130850

COc1c(O)c(CO)c(CO)c(O)c1OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.50
CA4 P22748 2/20 0.50
TDP1 Q9NUW8 1/20 0.40
AKR1B1 P15121 1/20 0.38
ERBB2 P04626 1/20 0.36
PIM1 P11309 1/20 0.36
HKDC1 Q2TB90 1/20 0.36
DRD4 P21917 1/20 0.35
MAPT P10636 2/20 0.33
CYP3A4 P08684 1/20 0.33
IMPDH2 P12268 2/20 0.33
PDE4A P27815 3/20 0.32
PDE4B Q07343 3/20 0.32
PDE4C Q08493 3/20 0.32
PDE4D Q08499 3/20 0.32
CA1 P00915 1/20 0.32
CA6 P23280 1/20 0.32
PDE1A P54750 3/20 0.32
PDE1B Q01064 3/20 0.32
PDE3B Q13370 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10130972 0.79 CA2 (0.42) CA2CA4AKR1B1IMPDH2PDE4A
SCHEMBL9108639 0.77 CA2 (0.54) CA2CA4TDP1AKR1B1MAPT
SCHEMBL13431191 0.75 CA2 (0.43) CA2CA4TDP1AKR1B1DRD4
SCHEMBL11260594 0.75 TDP1 (0.53) CA2CA4TDP1MAPTCYP3A4
SCHEMBL13864175 0.73 CYP3A4 (0.45) AKR1B1MAPTCYP3A4PDE4APDE4B
SCHEMBL7361916 0.72 IMPDH2 (0.46) CA2CA4TDP1IMPDH2IMPDH1
SCHEMBL17431561 0.72 IMPDH2 (0.37) CA2CA4TDP1AKR1B1IMPDH2
SCHEMBL2091785 0.72 TDP1 (0.50) TDP1MAPTCYP3A4PDE4APDE4B
SCHEMBL2620983 0.71 CA2 (0.36) CA2CA4AKR1B1IMPDH2IMPDH1
SCHEMBL13605942 0.71 AKR1B1 (0.41) CA2CA4TDP1AKR1B1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120077345-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-29 US disclosed
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2010-12-16 US disclosed
US-7476476-B2 Photosensitive resin composition, electronic component using the same, and display unit using the same TORAY INDUSTRIES, INC. (JP) 2009-01-13 US disclosed
US-20080075999-A1 Polyelectrolyte Material, Polyelectrolyte Component, Membrane Electrode Composite Body, and Polyelectrolyte Type Fuel Cell TORAY INDUSTRIES, INC. (JP) 2008-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION ICAM1, ESD, CAD CA2 2927/4885CA4 1392/4885TDP1 3162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.