Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708608 | 0.86 | POLB (0.38) | L3MBTL1KMT2AMEN1TSHRPOLB | |
| SCHEMBL11782537 | 0.84 | ALDH1A1 (0.49) | L3MBTL1KMT2AMEN1TSHRPOLB | |
| SCHEMBL11782542 | 0.84 | ALDH1A1 (0.49) | L3MBTL1KMT2APOLBMAPK1SMN1; SMN2 | |
| SCHEMBL28823865 | 0.82 | RAPGEF4 (0.38) | L3MBTL1KMT2AMEN1TSHRPOLB | |
| SCHEMBL5552179 | 0.81 | KAT6A (0.44) | L3MBTL1KMT2AMEN1TSHRPOLB | |
| SCHEMBL7185812 | 0.80 | L3MBTL1 (0.48) | L3MBTL1KMT2ATSHRPOLBCA1 | |
| SCHEMBL3649899 | 0.79 | MCOLN3 (0.50) | L3MBTL1KMT2AMEN1TSHRPOLB | |
| SCHEMBL21815478 | 0.79 | MEN1 (0.47) | L3MBTL1KMT2AMEN1TSHRPOLB | |
| SCHEMBL29118330 | 0.78 | AKR1B1 (0.35) | L3MBTL1KMT2AMEN1TSHRPOLB | |
| SCHEMBL28372969 | 0.77 | CA1 (0.37) | L3MBTL1KMT2AMEN1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036012-B | Pyrido [3,4-d ] pyrimidine derivatives and pharmaceutically acceptable salts thereof | 帝人制药株式会社 | 2022-05-10 | — | — | CN | disclosed |
| EP-2157859-A1 | INDAZOLE COMPOUNDS FOR ACTIVATING GLUCOKINASE | Takeda Pharmaceutical Company Limited (JP) | 2010-03-03 | — | — | EP | disclosed |
| WO-2008156757-A1 | INDAZOLE COMPOUNDS FOR ACTIVATING GLUCOKINASE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-24 | — | — | WO | disclosed |