Milveterol

Milveterol

SCHEMBL265694

O=CNc1cc([C@@H](O)CNCCc2ccc(NC[C@H](O)c3ccccc3)cc2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB2

The experimentally established mechanism targets of Milveterol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADRB2 known ✓ P07550 19/20 1.00
ADRB1 P08588 5/20 1.00
ADRB3 P13945 4/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Milveterol SCHEMBL168972 1.00 ADRB2 (1.00) ADRB2ADRB1ADRB3
Milveterol SCHEMBL265695 1.00 ADRB2 (1.00) ADRB2ADRB1ADRB3
Milveterol SCHEMBL4385046 1.00 ADRB2 (1.00) ADRB2ADRB1ADRB3
Milveterol SCHEMBL185356 1.00 ADRB2 (1.00) ADRB2ADRB1ADRB3
Milveterol SCHEMBL29448200 1.00 ADRB2 (1.00) ADRB2ADRB1ADRB3
Milveterol SCHEMBL2953766 0.99 ADRB2 (0.98) ADRB2ADRB1ADRB3
Milveterol SCHEMBL2953771 0.99 ADRB2 (0.98) ADRB2ADRB1ADRB3
Milveterol SCHEMBL2014102 0.99 ADRB2 (0.98) ADRB2ADRB1ADRB3
Milveterol SCHEMBL2014100 0.99 ADRB2 (0.98) ADRB2ADRB1ADRB3
Milveterol SCHEMBL2014099 0.99 ADRB2 (0.98) ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 645 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642463-A1 PHARMACEUTICAL COMPOSITIONS OF GREEN PROPELLANT Cipla Limited (IN) 2025-11-05 EP claimed
US-20250312274-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER CHIESI FARMACEUTICI S.P.A. (IT) 2025-10-09 US claimed
US-20250302742-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER CHIESI FARMACEUTICI S.P.A. (IT) 2025-10-02 US claimed
EP-4531920-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER Chiesi Farmaceutici S.p.A. (IT) 2025-04-09 EP claimed
EP-4531921-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER Chiesi Farmaceutici S.p.A. (IT) 2025-04-09 EP claimed
EP-4531922-A1 A PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER Chiesi Farmaceutici S.p.A. (IT) 2025-04-09 EP claimed
US-20250082588-A1 PHARMACEUTICAL FORMULATION FOR PRESSURISED METERED DOSE INHALER CHIESI FARMACEUTICI S.P.A. (IT) 2025-03-13 US claimed
US-20250057764-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR AEROSOL DRUG DELIVERY ASTRAZENECA AB (SE) 2025-02-20 US claimed
US-20240358662-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR AEROSOL DRUG DELIVERY ASTRAZENECA PHARMACEUTICALS LP (US) 2024-10-31 US claimed
EP-4452230-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR AEROSOL DRUG DELIVERY Astrazeneca AB (SE) 2024-10-30 EP claimed
US-20070155990-A1 Crystalline form of beta2 adrenergic receptor agonist THERAVANCE BIOPHARMA R&D IP, LLC 2007-07-05 US claimed
US-20070112027-A1 Crystalline forms of a biphenyl compound THERAVANCE, INC. 2007-05-17 US claimed
JP-2007500233-A 2007-01-11 JP claimed
WO-2006124556-A2 INHALABLE PHARMACEUTICAL FORMULATIONS EMPLOYING LACTOSE ANHYDRATE AND METHODS OF ADMINISTERING THE SAME GLAXO GROUP LIMITED (GB) 2006-11-23 WO claimed
EP-1641744-A2 CRYSTALLINE FORM OF B2 ADRENERGIC RECEPTOR AGONIST Theravance, Inc. (US) 2006-04-05 EP claimed
WO-2005123670-A2 CRYSTALLINE FORM OF A SUBSTITUTED PYRROLIDINE COMPOUND THERAVANCE, INC. (US) 2005-12-29 WO claimed
US-20050277688-A1 Crystalline form of a substituted pyrrolidine compound THERAVANCE, INC. 2005-12-15 US claimed
US-20050075271-A1 Crystalline beta2 adrenergic receptor agonist THERAVANCE, INC. 2005-04-07 US claimed
WO-2004106279-A2 CRYSTALLINE FORM OF β2 ADRENERGIC RECEPTOR AGONIST THERAVANCE, INC. (US) 2004-12-09 WO claimed
US-20040248985-A1 Crystalline form of beta2 adrenergic receptor agonist THERAVANCE BIOPHARMA R&D IP, LLC 2004-12-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050277688-A1 Crystalline form of a substituted pyrrolidine compound PKD2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PKD1 ADRB2 3122/4885ADRB1 3252/4885ADRB3 3374/4885
US-20070112027-A1 Crystalline forms of a biphenyl compound FFAR1, FFAR4, FFAR3 ADRB2 2730/4885ADRB1 1439/4885ADRB3 2164/4885
US-20040248985-A1 Crystalline form of beta2 adrenergic receptor agonist ADRB2, ADRA2C, ADRA2A ADRB2 1/4885ADRB1 4/4885ADRB3 6/4885
US-20070155990-A1 Crystalline form of beta2 adrenergic receptor agonist ADRB2, ADRA2C, ADRA2A ADRB2 1/4885ADRB1 4/4885ADRB3 6/4885
US-20050075271-A1 Crystalline beta2 adrenergic receptor agonist ADRB2, ADRA2C, ADRA2A ADRB2 1/4885ADRB1 4/4885ADRB3 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.