SCHEMBL26569584

SCHEMBL26569584

CN1CCN(C(=O)C(OC(=O)O)c2ccc(NC(=O)CNC(=O)C3(C(=O)NCCCCCN4C(=O)C=CC4=O)CCC3)cc2)CC1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ FPR3 P25089 3/20 0.33
▸ FPR2 P25090 3/20 0.33
▸ CHRM1 P11229 1/20 0.33
▸ RAB9A P51151 1/20 0.31
▸ OPRM1 P35372 1/20 0.31
▸ OPRD1 P41143 1/20 0.31
▸ OPRK1 P41145 1/20 0.31
▸ LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25227173 0.85 SIRT1 (0.30) —
SCHEMBL26566023 0.85 SIRT1 (0.30) —
Trifluoroacetic Acid SCHEMBL25233000 0.82 SIRT1 (0.30) —
SCHEMBL25216180 0.80 FAP (0.31) —
SCHEMBL20830999 0.78 OPRM1 (0.36) FPR3FPR2RAB9AOPRM1OPRD1
SCHEMBL19683911 0.78 OPRM1 (0.36) FPR3FPR2RAB9AOPRM1OPRD1
Trifluoroacetic Acid SCHEMBL25205346 0.78 FAP (0.30) —
SCHEMBL23020008 0.76 OPRM1 (0.35) RAB9AOPRM1OPRD1OPRK1LMNA
SCHEMBL26565879 0.72 — —
SCHEMBL26563684 0.71 SIRT1 (0.33) FPR3FPR2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230330249-A1 ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION OF BRM AND METHODS THEREOF GENENTECH, INC. (US) 2023-10-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330249-A1 ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION OF BRM AND METHODS THEREOF ADRM1, CD79B, BRDT FPR3 3229/4885FPR2 3180/4885CHRM1 1532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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