Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 3/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17301594 | 0.89 | MEN1 (0.58) | NPC1RAB9AMAPK1SMN1; SMN2NFKB1 | |
| SCHEMBL970559 | 0.89 | NPC1 (0.62) | NPC1RAB9AMAPK1SMN1; SMN2NFKB1 | |
| SCHEMBL17190530 | 0.89 | MEN1 (0.58) | NPC1RAB9AMAPK1SMN1; SMN2NFKB1 | |
| SCHEMBL31222447 | 0.80 | IDO1 (0.45) | NPC1MAPK1SMN1; SMN2HPGDSPDGFRB | |
| SCHEMBL31222449 | 0.80 | IDO1 (0.45) | NPC1MAPK1SMN1; SMN2HPGDSPDGFRB | |
| SCHEMBL13150188 | 0.78 | METAP2 (0.47) | NPC1RAB9AMAPK1SMN1; SMN2NFKB1 | |
| SCHEMBL1104825 | 0.76 | NPC1 (0.54) | NPC1RAB9AMAPK1SMN1; SMN2NFKB1 | |
| SCHEMBL837812 | 0.76 | MEN1 (0.48) | NPC1RAB9ASMN1; SMN2PTGESPDGFRB | |
| SCHEMBL20286582 | 0.76 | MAPT (0.50) | NPC1RAB9ASMN1; SMN2PTGESPDGFRB | |
| SCHEMBL12015944 | 0.76 | ADORA2A (0.48) | PTGESMAPTHSD17B10GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230332197-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP | ILLUMINA, INC. | 2023-10-19 | — | — | US | disclosed |
| CN-108586369-B | Process for producing phenyltriazine compound and process for producing phenylpyridine compound | 中国科学院长春应用化学研究所 | 2021-08-17 | — | — | CN | disclosed |
| CN-108586369-A | The preparation method of phenyl triaizine compounds and the preparation method of phenylpyridine compound | 中国科学院长春应用化学研究所 | 2018-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230332197-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP | NT5C3B, NSUN2, DUT | NPC1 2987/4885RAB9A 2767/4885MAPK1 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.