Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HPGDS | O60760 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26569790 | 0.76 | NPC1 (0.56) | NPC1RAB9AMAPK1NFKB1NFKB2 | |
| SCHEMBL17055412 | 0.75 | NPC1 (0.53) | NPC1RAB9AMAPK1NFKB1NFKB2 | |
| SCHEMBL436106 | 0.75 | NPC1 (0.65) | NPC1RAB9AMAPK1NFKB1NFKB2 | |
| SCHEMBL3652642 | 0.72 | NPC1 (1.00) | NPC1RAB9AMAPK1NFKB1NFKB2 | |
| SCHEMBL17055434 | 0.72 | NPC1 (0.55) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL11978673 | 0.72 | NPC1 (0.74) | NPC1RAB9AMAPK1NFKB1NFKB2 | |
| SCHEMBL17055377 | 0.71 | NPC1 (0.67) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL17055440 | 0.71 | NPC1 (0.74) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL10091200 | 0.71 | NPC1 (0.67) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL14864992 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-07-25 | — | — | US | disclosed |
| EP-4329889-A1 | IL4I1 INHIBITORS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2024-03-06 | — | — | EP | disclosed |
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2023-07-04 | — | — | US | disclosed |
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2023-07-04 | — | — | US | disclosed |
| WO-2022227015-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2022-11-03 | — | — | WO | disclosed |
| WO-2022232333-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2022-11-03 | — | — | WO | disclosed |
| US-11069862-B2 | Material for organic electroluminescence device and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2021-07-20 | — | — | US | disclosed |
| US-10833281-B2 | Organic electroluminescence composition, material for organic electroluminescence element, solution of material for organic electroluminescence element, and organic electroluminescence element | IDEMITSU KOSAN CO., LTD. (JP) | 2020-11-10 | — | — | US | disclosed |
| US-10707434-B2 | Organic electroluminescence element, and material for organic electroluminescence element | IDEMITSU KOSAN CO., LTD. (JP) | 2020-07-07 | — | — | US | disclosed |
| US-10622569-B2 | Compound, organic electroluminescent element, and electronic device | IDEMITSU KOSAN CO., LTD. (JP) | 2020-04-14 | — | — | US | disclosed |
| US-20080100207-A1 | Organoelectroluminescent compound and organoelectroluminescent device employing the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2008-05-01 | — | — | US | disclosed |
| US-7354924-B2 | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-08 | — | — | US | disclosed |
| US-20080079356-A1 | Organoelectroluminescent compound and organoelectroluminescent device employing the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2008-04-03 | — | — | US | disclosed |
| US-20080079356-A1 | Organoelectroluminescent compound and organoelectroluminescent device employing the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2008-04-03 | — | — | US | disclosed |
| US-20080076942-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-03-27 | — | — | US | disclosed |
| US-20080076942-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-03-27 | — | — | US | disclosed |
| US-20070273270-A1 | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2007-11-29 | — | — | US | disclosed |
| US-20070273270-A1 | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2007-11-29 | — | — | US | disclosed |
| US-20070275266-A1 | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2007-11-29 | — | — | US | disclosed |
| US-20070275266-A1 | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076942-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | TYR, MAOA, DDC | NPC1 4722/4885RAB9A 2826/4885MAPK1 2203/4885 |
| US-10833281-B2 | Organic electroluminescence composition, material for organic electroluminescence element, solution of material for organic electroluminescence element, and organic electroluminescence element | SLCO4C1, SLCO2A1, SLCO1A2 | NPC1 648/4885RAB9A 2190/4885MAPK1 1896/4885 |
| US-11069862-B2 | Material for organic electroluminescence device and organic electroluminescence device using the same | EPCAM, ILK, PPOX | NPC1 3774/4885RAB9A 2255/4885MAPK1 915/4885 |
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | KCNQ2, KCNQ1, KCNQ4 | NPC1 2663/4885RAB9A 2910/4885MAPK1 3128/4885 |
| US-20080100207-A1 | Organoelectroluminescent compound and organoelectroluminescent device employing the same | PPOX, EML4, DDT | NPC1 2476/4885RAB9A 1313/4885MAPK1 3547/4885 |
| US-10622569-B2 | Compound, organic electroluminescent element, and electronic device | EFNA1, L1CAM, LEF1 | NPC1 1796/4885RAB9A 502/4885MAPK1 294/4885 |
| US-10707434-B2 | Organic electroluminescence element, and material for organic electroluminescence element | LEF1, L1CAM, AGO2 | NPC1 2824/4885RAB9A 1106/4885MAPK1 305/4885 |
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | IL4I1, IL4, IL2 | NPC1 2807/4885RAB9A 3769/4885MAPK1 749/4885 |
| US-20080079356-A1 | Organoelectroluminescent compound and organoelectroluminescent device employing the same | PPOX, EML4, ALPL | NPC1 2358/4885RAB9A 1006/4885MAPK1 3397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.