SCHEMBL26570916

SCHEMBL26570916

Fc1ccc(-c2ccc(-c3ccc4cc(-c5ccc(-c6ccc(C7CC7)cc6)cc5)cnc4c3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 7/20 0.49
PDGFRA P16234 7/20 0.49
ESR2 Q92731 1/20 0.45
GRIN2B Q13224 5/20 0.42
GAK O14976 1/20 0.40
GPR55 Q9Y2T6 1/20 0.40
MCHR1 Q99705 1/20 0.40
BCL9 O00512 2/20 0.39
CTNNB1 P35222 2/20 0.39
JAK2 O60674 1/20 0.38
DHODH Q02127 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26549437 0.86 PDGFRB (0.61) PDGFRBPDGFRAESR2GAK
SCHEMBL26549163 0.86 PDGFRB (0.61) PDGFRBPDGFRAESR2GAK
SCHEMBL26570926 0.85 HTR2C (0.43) PDGFRBPDGFRAESR2GAK
SCHEMBL26566340 0.83 PTGS2 (0.43) ESR2DHODH
SCHEMBL26549330 0.79 PDGFRB (0.54) PDGFRBPDGFRAESR2GAK
SCHEMBL26549064 0.79 PDGFRB (0.62) PDGFRBPDGFRAESR2GAK
SCHEMBL26549364 0.79 PDGFRB (0.58) PDGFRBPDGFRAESR2GAK
SCHEMBL26570909 0.79 PDGFRB (0.57) PDGFRBPDGFRAESR2GAK
SCHEMBL26549357 0.79 PDGFRB (0.62) PDGFRBPDGFRAESR2GAK
SCHEMBL26549071 0.79 PDGFRB (0.58) PDGFRBPDGFRAESR2GAK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 PDGFRB 4867/4885PDGFRA 4853/4885ESR2 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.