Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.85 |
| ▸ | RAB9A | P51151 | 2/20 | 0.85 |
| ▸ | NPC1 | O15118 | 1/20 | 0.85 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.72 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.69 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399487 | 0.92 | RAB9A (1.00) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL30692090 | 0.92 | RAB9A (1.00) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL27506 | 0.90 | SRD5A2 (0.81) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL31456551 | 0.90 | SRD5A2 (0.81) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| Hydrochloric Acid SCHEMBL9789481 | 0.88 | SRD5A2 (0.79) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL11841857 | 0.87 | MAPT (0.89) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL30976964 | 0.85 | SRD5A2 (0.79) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL1647589 | 0.85 | SRD5A2 (0.79) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL407340 | 0.84 | MAPT (0.82) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL26575457 | 0.84 | RAB9A (0.82) | MAPTRAB9ANPC1HSD17B1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230330045-A1 | THE ANTIVIRAL DRUG TILORONE IS A POTENT AND SELECTIVE INHIBITOR OF ACETYLCHOLINESTERASE | COLLABORATIONS PHARMACEUTICALS, INC. | 2023-10-19 | — | — | US | disclosed |
| US-20230330045-A1 | THE ANTIVIRAL DRUG TILORONE IS A POTENT AND SELECTIVE INHIBITOR OF ACETYLCHOLINESTERASE | COLLABORATIONS PHARMACEUTICALS, INC. | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230330045-A1 | THE ANTIVIRAL DRUG TILORONE IS A POTENT AND SELECTIVE INHIBITOR OF ACETYLCHOLINESTERASE | ACHE, BCHE, ACE | MAPT 886/4885RAB9A 2916/4885NPC1 3609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.