Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.82 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30692090 | 1.00 | RAB9A (1.00) | RAB9ANPC1MAPTHSD17B1SRD5A2 | |
| SCHEMBL11841857 | 0.94 | MAPT (0.89) | RAB9ANPC1MAPTHSD17B1SRD5A2 | |
| SCHEMBL26575463 | 0.92 | MAPT (0.85) | RAB9ANPC1MAPTHSD17B1SRD5A2 | |
| SCHEMBL407340 | 0.91 | MAPT (0.82) | RAB9ANPC1MAPTHSD17B1SRD5A2 | |
| SCHEMBL4945231 | 0.91 | HSD17B1 (1.00) | RAB9ANPC1MAPTHSD17B1SRD5A2 | |
| SCHEMBL26575457 | 0.91 | RAB9A (0.82) | RAB9ANPC1MAPTHSD17B1SRD5A2 | |
| SCHEMBL26185760 | 0.89 | RAB9A (0.79) | RAB9ANPC1MAPTHSD17B1SRD5A2 | |
| SCHEMBL5048102 | 0.89 | RAB9A (0.79) | RAB9ANPC1MAPTHSD17B1SRD5A2 | |
| SCHEMBL11839424 | 0.89 | RAB9A (0.79) | RAB9ANPC1MAPTHSD17B1SRD5A2 | |
| SCHEMBL15202656 | 0.89 | MAPT (0.80) | RAB9ANPC1MAPTHSD17B1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117264181-A | Preparation method and application of PTSA (Positive temperature coefficient) catalyzed green porous organic polymer under solvent-free condition | 潍坊医学院附属医院 | 2023-12-22 | — | — | CN | claimed |
| CN-104603215-A | Composition for coating high refractive layer and transparent conductive film comprising same | LG HAUSYS LTD | 2015-05-06 | — | — | CN | claimed |
| CN-117264181-B | Preparation method and application of PTSA (Positive temperature coefficient) catalyzed green porous organic polymer under solvent-free condition | 潍坊医学院附属医院 | 2024-01-26 | — | — | CN | disclosed |
| CN-117264181-A | Preparation method and application of PTSA (Positive temperature coefficient) catalyzed green porous organic polymer under solvent-free condition | 潍坊医学院附属医院 | 2023-12-22 | — | — | CN | disclosed |
| US-20230330045-A1 | THE ANTIVIRAL DRUG TILORONE IS A POTENT AND SELECTIVE INHIBITOR OF ACETYLCHOLINESTERASE | COLLABORATIONS PHARMACEUTICALS, INC. | 2023-10-19 | — | — | US | disclosed |
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |
| US-9770439-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-26 | — | — | US | disclosed |
| US-20160199355-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MAYERS SQUIBB COMPANY (US) | 2016-07-14 | — | — | US | disclosed |
| US-20160158200-A1 | Combinations of Hepatitis C Virus Inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2016-06-09 | — | — | US | disclosed |
| US-9326973-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-05-03 | — | — | US | disclosed |
| EP-0666267-B1 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2001019792-A1 | COVALENTLY LINKED DIMERIC DNA BINDING MOLECULES | GENELABS TECHNOLOGIES, INC. (US) | 2001-03-22 | — | — | WO | disclosed |
| CN-1060176-C | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2001-01-03 | — | — | CN | disclosed |
| US-5668230-A | METALLOCENE WITH ETHYLENE BRIDGED FLUORENE UNITS, ALUMOXANE COCATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| US-5571880-A | CATALYSTS FOR POLYMERIZATION OF OLEFINS ESPECIALLY TO OBTAIN SYNDIOTACTIC POLYMERS | PHILLIPS PETROLEUM COMPANY (US) | 1996-11-05 | — | — | US | disclosed |
| CN-1109472-A | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 1995-10-04 | — | — | CN | disclosed |
| EP-0666267-A2 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-08-09 | — | — | EP | disclosed |
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |
| US-3939276-A | ANTHRAQUINONES, ASTHMA, ANTIALLERGENS | BURROUGHS WELLCOME CO. (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160199355-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, MAVS, EIF2AK2 | RAB9A 1490/4885NPC1 414/4885MAPT 3132/4885 |
| US-20160158200-A1 | Combinations of Hepatitis C Virus Inhibitors | HAVCR2, EIF2AK2, MAVS | RAB9A 1807/4885NPC1 706/4885MAPT 3548/4885 |
| US-20230330045-A1 | THE ANTIVIRAL DRUG TILORONE IS A POTENT AND SELECTIVE INHIBITOR OF ACETYLCHOLINESTERASE | ACHE, BCHE, ACE | RAB9A 2916/4885NPC1 3609/4885MAPT 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.