Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2659952 | 0.84 | CYP1A2 (0.35) | LMNANPSR1MAPT | |
| SCHEMBL2659763 | 0.84 | CYP1A2 (0.35) | LMNANPSR1MAPT | |
| SCHEMBL2660323 | 0.84 | CYP1A2 (0.35) | LMNANPSR1MAPT | |
| SCHEMBL2659288 | 0.80 | SHBG (0.34) | LMNANPSR1MAPT | |
| SCHEMBL2658653 | 0.80 | SHBG (0.34) | LMNANPSR1MAPT | |
| SCHEMBL2659785 | 0.80 | SHBG (0.34) | LMNANPSR1MAPT | |
| SCHEMBL2658566 | 0.77 | MAPT (0.39) | EPHX2NPSR1MAPT | |
| SCHEMBL2659555 | 0.77 | MAPT (0.39) | EPHX2NPSR1MAPT | |
| SCHEMBL2660197 | 0.77 | MAPT (0.39) | EPHX2NPSR1MAPT | |
| SCHEMBL2658753 | 0.75 | EPHX1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904466-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | Novo Nordisk A/S (DK) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007006760-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |