SCHEMBL26596972

SCHEMBL26596972

CC(C)(C)n1c(N)cc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
CA12 O43570 3/20 0.34
CA9 Q16790 3/20 0.34
BRD4 O60885 1/20 0.34
BRPF1 P55201 1/20 0.34
KAT2B Q92831 1/20 0.34
BRD9 Q9H8M2 1/20 0.34
DAO P14920 2/20 0.34
MCL1 Q07820 1/20 0.34
ALOX5AP P20292 1/20 0.33
SLC9A1 P19634 1/20 0.33
KDM4E B2RXH2 2/20 0.33
HPGD P15428 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.33
TP53 P04637 1/20 0.32
TERT O14746 1/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26627965 0.82 DHFR (0.38) KMT2AKDM4EHPGDALDH1A1MEN1
SCHEMBL26597055 0.78 DAO (0.41) KMT2ACA12CA9BRD4BRPF1
SCHEMBL7756916 0.78 KDM4E (0.42) KMT2ADAOMCL1KDM4EHPGD
SCHEMBL7638728 0.76 HDAC10 (0.40) KMT2ACA12CA9BRD4BRPF1
SCHEMBL26596994 0.74 ALOX5AP (0.40) ALOX5APKDM4EMAPTKCNH2
SCHEMBL26596989 0.74 ALOX5AP (0.40) ALOX5APMAPTCYP3A4
SCHEMBL26597059 0.74 GAA (0.41) KMT2AKDM4EHPGDALDH1A1HSD17B10
SCHEMBL19135849 0.73 DHFR (0.43) KMT2AHTR2AHTR2C
SCHEMBL14929532 0.73 KMT2A (0.59) KMT2AKDM4EHPGDALDH1A1MEN1
SCHEMBL10247449 0.73 KMT2A (0.38) KMT2ADAOMCL1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof Lakewood Amedex, Inc. (US) 2023-10-24 US disclosed
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof Lakewood Amedex, Inc. (US) 2023-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof CAT, MPO, NISCH KMT2A 4874/4885CA12 3608/4885CA9 987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.