Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2659597 | 0.73 | RIPK1 (0.44) | RIPK1ALDH1A1KMT2APYCR1YAP1 | |
| SCHEMBL13153417 | 0.67 | RIPK1 (0.44) | RIPK1SLC6A2SLC6A4SLC6A3TRPA1 | |
| SCHEMBL2660021 | 0.66 | MEN1 (0.47) | SLC6A2SLC6A4SLC6A3ALDH1A1KMT2A | |
| SCHEMBL16312137 | 0.64 | PYCR1 (0.46) | SLC6A2SLC6A4SLC6A3TRPA1ALDH1A1 | |
| SCHEMBL13181109 | 0.64 | ALDH1A1 (0.46) | RIPK1SLC6A2SLC6A4SLC6A3TRPA1 | |
| SCHEMBL13532083 | 0.63 | PYCR1 (0.48) | RIPK1SLC6A2SLC6A4SLC6A3TRPA1 | |
| SCHEMBL10294050 | 0.63 | RIPK1 (0.50) | RIPK1ALDH1A1PYCR1TDP1ESR1 | |
| SCHEMBL2660391 | 0.62 | HRH4 (0.41) | SLC6A2SLC6A4SLC6A3ALDH1A1KMT2A | |
| SCHEMBL14350226 | 0.62 | MCHR1 (0.42) | RIPK1SLC6A2SLC6A4ALDH1A1KMT2A | |
| SCHEMBL19598855 | 0.62 | IDO1 (0.45) | TRPA1ALDH1A1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097557-A1 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | DUFFY JOSEPH L (US) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097557-A1 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | GLP1R, GPR119, GCGR | RIPK1 1655/4885SLC6A2 771/4885SLC6A4 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.