Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 11/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2659649 | 0.91 | SLC40A1 (0.45) | SLC40A1KMT2ATDP1MEN1NSD2 | |
| SCHEMBL2660199 | 0.90 | SLC40A1 (0.46) | SLC40A1KMT2ATDP1MEN1NSD2 | |
| SCHEMBL2659240 | 0.86 | POLB (0.50) | SLC40A1KMT2ATDP1MEN1NSD2 | |
| SCHEMBL2662137 | 0.81 | SLC40A1 (0.54) | SLC40A1KMT2ATDP1MEN1NFKBIA | |
| SCHEMBL2659586 | 0.81 | MAPT (0.36) | SLC40A1KMT2ATDP1MEN1SETD2 | |
| SCHEMBL1654857 | 0.79 | TUBB4A (0.48) | SLC40A1KMT2ATDP1MEN1MAPT | |
| SCHEMBL2660410 | 0.77 | SLC40A1 (0.46) | SLC40A1KMT2ATDP1MEN1NFKBIA | |
| SCHEMBL2660294 | 0.77 | NSD2 (0.37) | KMT2AMEN1NSD2 | |
| SCHEMBL2660464 | 0.77 | MMP2 (0.49) | SLC40A1KMT2ATDP1MEN1NFKBIA | |
| SCHEMBL2659265 | 0.77 | TUBB4A (0.36) | SLC40A1KMT2AMEN1NSD2NFKBIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |