SCHEMBL2659920

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2661679	0.89	KMT2A (0.38)	KDM4ENPC1ALDH1A1LMNAHPGD
	SCHEMBL13221345	0.87	MCL1 (0.39)	LMNAHPGDPIK3C3MCL1KMT2A
	SCHEMBL13348445	0.84	MCL1 (0.38)	PIK3C3MCL1
	SCHEMBL2660818	0.83	SLC40A1 (0.42)	KDM4ENPC1ALDH1A1LMNAHPGD
	SCHEMBL2668701	0.83	KDM4E (0.36)	KDM4ENPC1ALDH1A1LMNAHPGD
	SCHEMBL2660059	0.82	ALDH1A1 (0.46)	ALDH1A1LMNAHPGDPOLBKMT2A
	SCHEMBL2660569	0.82	ALDH1A1 (0.39)	KDM4ENPC1ALDH1A1LMNAHPGD
	SCHEMBL2661682	0.82	KDM4E (0.37)	KDM4ENPC1ALDH1A1LMNAHPGD
	SCHEMBL2660459	0.80	TRIM24 (0.32)	KDM4EALDH1A1LMNAHPGDKMT2A
	SCHEMBL2659926	0.79	SLC40A1 (0.41)	KDM4ENPC1ALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.