Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NGFR | P08138 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2661679 | 0.91 | KMT2A (0.38) | KDM4EALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL2661453 | 0.81 | ITGB3 (0.34) | SYKKDM4EMAPT | |
| SCHEMBL2659920 | 0.80 | KDM4E (0.37) | KDM4EALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL2659522 | 0.79 | SLC40A1 (0.38) | ALDH1A1LMNAHPGDKMT2ATP53 | |
| SCHEMBL2659731 | 0.78 | METAP2 (0.43) | — | |
| SCHEMBL2659829 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HPGDKMT2A | |
| SCHEMBL2661084 | 0.78 | MCL1 (0.33) | KDM4EALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL13083415 | 0.76 | KDM4E (0.42) | KDM4EALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL13221345 | 0.75 | MCL1 (0.39) | TRIM24LMNAHPGDKMT2ATP53 | |
| SCHEMBL2659714 | 0.74 | SLC40A1 (0.38) | TRIM24ALDH1A1LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |