Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.73 |
| ▸ | DRD3 | P35462 | 3/20 | 0.73 |
| ▸ | HTR3A | P46098 | 2/20 | 0.73 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.73 |
| ▸ | HTR3B | O95264 | 1/20 | 0.73 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | HTR6 | P50406 | 1/20 | 0.73 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.73 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.73 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | HTR7 | P34969 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 4/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11620055 | 0.90 | DRD2 (0.84) | DRD2DRD3HTR3AHTR3EHTR3B | |
| SCHEMBL6366499 | 0.85 | HTR3A (1.00) | DRD2DRD3HTR3AHTR3EHTR3B | |
| SCHEMBL29396943 | 0.85 | HTR3A (1.00) | DRD2DRD3HTR3AHTR3EHTR3B | |
| SCHEMBL379 | 0.85 | HTR3A (1.00) | DRD2DRD3HTR3AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL246416 | 0.84 | LMNA (1.00) | DRD2DRD3HTR3AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL6602545 | 0.84 | LMNA (1.00) | DRD2DRD3HTR3AHTR3EHTR3B | |
| Piperazine SCHEMBL28843777 | 0.84 | HTR3A (0.96) | DRD2DRD3HTR3AHTR3EHTR3B | |
| Bromide SCHEMBL27797305 | 0.84 | HTR3A (0.96) | DRD2DRD3HTR3AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL29397565 | 0.84 | LMNA (1.00) | DRD2DRD3HTR3AHTR3EHTR3B | |
| Alcohol SCHEMBL7289118 | 0.83 | DRD2 (0.87) | DRD2DRD3HTR3AHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12454547-B2 | Steroidal compositions and methods of treating lipogenic cancers | Asteroid Therapeutics (US) | 2025-10-28 | — | — | US | disclosed |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
| WO-2023205801-A2 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics (US) | 2023-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12454547-B2 | Steroidal compositions and methods of treating lipogenic cancers | SREBF1, SREBF2, NR1H3 | DRD2 4843/4885DRD3 4708/4885HTR3A 4389/4885 |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | SREBF1, SREBF2, NR1H3 | DRD2 4843/4885DRD3 4708/4885HTR3A 4389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.