Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | CASP3 | P42574 | 2/20 | 0.64 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.61 |
| ▸ | ACP1 | P24666 | 5/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28979085 | 0.90 | PTPN1 (0.60) | MEN1KMT2APOLBCASP3SENP8 | |
| SCHEMBL29411713 | 0.90 | PTPN1 (0.60) | MEN1KMT2APOLBCASP3SENP8 | |
| SCHEMBL26709485 | 0.90 | PTPN1 (0.60) | MEN1KMT2APOLBCASP3SENP8 | |
| SCHEMBL15682752 | 0.89 | MEN1 (0.78) | MEN1KMT2APOLBCASP3SENP8 | |
| SCHEMBL28978724 | 0.88 | ENPP2 (0.53) | MEN1KMT2APOLBCASP3SENP8 | |
| SCHEMBL26709495 | 0.88 | ENPP2 (0.53) | MEN1KMT2APOLBCASP3SENP8 | |
| SCHEMBL29411674 | 0.88 | ENPP2 (0.53) | MEN1KMT2APOLBCASP3SENP8 | |
| SCHEMBL26709466 | 0.86 | NLRP3 (0.71) | MEN1KMT2APOLBCASP3SENP8 | |
| SCHEMBL28979066 | 0.86 | NLRP3 (0.71) | MEN1KMT2APOLBCASP3SENP8 | |
| SCHEMBL29411677 | 0.85 | ENPP2 (0.51) | MEN1KMT2APOLBCASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339871-A1 | COMPOUNDS AND METHODS OF MODULATING 17B-HYDROXYSTEROID DEHYDROGENASE TYPE 13 | METREA BIOSCIENCES INC (US) | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339871-A1 | COMPOUNDS AND METHODS OF MODULATING 17B-HYDROXYSTEROID DEHYDROGENASE TYPE 13 | HSD17B1, HSD17B13, HSD17B11 | MEN1 2186/4885KMT2A 2837/4885POLB 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.