Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.71 |
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | ACP1 | P24666 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26709466 | 1.00 | NLRP3 (0.71) | NLRP3PIM1MEN1POLBKMT2A | |
| SCHEMBL26709485 | 0.88 | PTPN1 (0.60) | NLRP3MEN1POLBKMT2AALDH1A1 | |
| SCHEMBL28979085 | 0.88 | PTPN1 (0.60) | NLRP3MEN1POLBKMT2AALDH1A1 | |
| SCHEMBL29411713 | 0.88 | PTPN1 (0.60) | NLRP3MEN1POLBKMT2AALDH1A1 | |
| SCHEMBL26606767 | 0.86 | MEN1 (0.64) | PIM1MEN1POLBKMT2AMAPK1 | |
| SCHEMBL29411695 | 0.85 | PIM1 (0.60) | NLRP3PIM1MEN1POLBKMT2A | |
| SCHEMBL26709501 | 0.85 | PIM1 (0.60) | NLRP3PIM1MEN1POLBKMT2A | |
| SCHEMBL29411674 | 0.84 | ENPP2 (0.53) | NLRP3PIM1MEN1POLBKMT2A | |
| SCHEMBL28978724 | 0.84 | ENPP2 (0.53) | NLRP3PIM1MEN1POLBKMT2A | |
| SCHEMBL26709495 | 0.84 | ENPP2 (0.53) | NLRP3PIM1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916762-A | Compounds and methods for modulating 17 beta-hydroxysteroid dehydrogenase type 13 | 梅特雷亚生物科学股份有限公司 | 2023-04-04 | — | — | CN | disclosed |