SCHEMBL266083

SCHEMBL266083

C=Cc1ccc(Cl)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL74726 0.79 NFE2L2 (0.50)
SCHEMBL74725 0.79 NFE2L2 (0.50)
SCHEMBL733566 0.76
SCHEMBL1311523 0.76
SCHEMBL74727 0.74 NFE2L2 (0.50)
SCHEMBL29440483 0.73 ALDH1A1 (0.48)
SCHEMBL16288697 0.73
SCHEMBL5789919 0.73 ALDH1A1 (0.48)
SCHEMBL30983654 0.73
SCHEMBL14878746 0.73 KDM4E (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112375308-A High-strength self-healing rubber material and preparation method thereof 侯光宇 2021-02-19 CN claimed
WO-2026087899-A1 MODULATORS OF THE GPR17 RECEPTOR NXERA PHARMA UK LIMITED (GB) 2026-04-30 WO disclosed
US-20250325552-A1 SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES INC (US) 2025-10-23 US disclosed
CN-117083271-A Substituted thiadiazolyl derivatives as DNA polymerase theta inhibitors 伊迪亚生物科学有限公司 2023-11-17 CN disclosed
EP-4255573-A1 SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS Ideaya Biosciences, Inc. (US) 2023-10-11 EP disclosed
WO-2022118210-A1 SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES, INC. (US) 2022-06-09 WO disclosed
WO-2022118210-A1 SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES, INC. (US) 2022-06-09 WO disclosed
CN-112375308-A High-strength self-healing rubber material and preparation method thereof 侯光宇 2021-02-19 CN disclosed
US-20170273985-A1 TRICYCLIC DERIVATIVE SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2017-09-28 US disclosed
US-20170273985-A1 TRICYCLIC DERIVATIVE SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2017-09-28 US disclosed
EP-0706536-B1 THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE, COMPOSITIONS CONTAINING THE SAME PROCTER & GAMBLE (US) 2000-05-17 EP disclosed
US-5980878-A A WATER OR ALCOHOL SOLUBLE OR DISPERSIBLE RANDOM COPOLYMERS COMPRISING A HYDROPHILIC MACROMONOMER UNITS HAVING UNSATURATED ALKYL QUATERNIZED NITROGEN GROUP; FOR HAIR STYLING, TOPICAL SKIN CARE FOR DRUG DELIVERY, TRANSDERMAL THE PROCTER & GAMBLE COMPANY (US) 1999-11-09 US disclosed
US-5919439-A USEFUL FOR DELIVERING AND/OR TRANSDERMALLY TRANSPORTING ACTIVE INGREDIENTS; HAIR STYLING THE PROCTER & GAMBLE COMPANY (US) 1999-07-06 US disclosed
US-5622694-A WATER OR ALCOHOL SOLUBLE THE PROCTER & GAMBLE COMPANY (US) 1997-04-22 US disclosed
CN-1133603-A Silicone grafted thermoplastic elastomeric copolymers and hair and skin care compositions containing the same PROCTER & GAMBLE (US) 1996-10-16 CN disclosed
CN-1129945-A Thermoplastic elastomeric copolymers and hair and skin care compositions containing the same PROCTER & GAMBLE (US) 1996-08-28 CN disclosed
EP-0715638-A1 SILICONE GRAFTED THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1996-06-12 EP disclosed
EP-0706536-A1 THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE, COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1996-04-17 EP disclosed
WO-1995006078-A1 SILICONE GRAFTED THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1995-03-02 WO disclosed
WO-1995001383-A1 THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE, COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1995-01-12 WO disclosed