⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4005376 | 0.83 | LTA4H (0.43) | — | |
| SCHEMBL30983654 | 0.82 | — | — | |
| SCHEMBL18921504 | 0.80 | NFE2L2 (0.51) | — | |
| SCHEMBL18921503 | 0.80 | NFE2L2 (0.51) | — | |
| SCHEMBL2458142 | 0.78 | HDAC3 (0.41) | — | |
| SCHEMBL16838770 | 0.78 | LTA4H (0.44) | — | |
| SCHEMBL266083 | 0.76 | — | — | |
| SCHEMBL1311523 | 0.76 | — | — | |
| SCHEMBL231541 | 0.76 | LTC4S (0.39) | — | |
| SCHEMBL30893537 | 0.75 | KCNJ1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 516 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111718327-B | Azacyclopyrimidine hydrazone Zn (II) complex containing multiple coordination sites as well as preparation method and application thereof | 河南中医药大学 | 2023-04-07 | — | — | CN | claimed |
| CN-114805637-B | Marine organism polysaccharide Schiff base derivative and preparation method and application thereof | 中国科学院海洋研究所 | 2023-02-03 | — | — | CN | claimed |
| CN-114805637-A | Marine organism polysaccharide Schiff base derivative and preparation method and application thereof | 中国科学院海洋研究所 | 2022-07-29 | — | — | CN | claimed |
| CN-114635137-A | Organic-inorganic hybrid composite corrosion inhibitor and preparation method and application thereof | 华南理工大学 | 2022-06-17 | — | — | CN | claimed |
| CN-111718327-A | Azacyclopyrimidine hydrazone Zn (II) complex containing multiple coordination sites as well as preparation method and application thereof | 河南中医药大学 | 2020-09-29 | — | — | CN | claimed |
| CN-110423234-B | Thiosemicarbazone derivative containing indole fragment and preparation method and application thereof | 郑州大学 | 2020-06-30 | — | — | CN | claimed |
| CN-110423234-A | Thiosemicarbazone derivative of the segment containing indoles and its preparation method and application | UNIV ZHENGZHOU | 2019-11-08 | — | — | CN | claimed |
| EP-2090576-A1 | 6-halo-pyrazolo[1,5-a]pyridines, a process for their preparation and their use as metabotropic glutamate receptor (mGluR) modulators | Merz Pharma GmbH & Co.KGaA (DE) | 2009-08-19 | — | — | EP | claimed |
| EP-1581525-A2 | COMPOUNDS HAVING AN ACTIVITY AT METABOTROPIC GLUTAMATE RECEPTORS | AstraZeneca AB (SE) | 2005-10-05 | — | — | EP | claimed |
| US-20040106607-A1 | New compounds | ASTRAZENECA AB AND NPS PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | claimed |
| WO-2004014902-A2 | COMPOUNDS HAVING AN ACTIVITY AT METABOTROPIC GLUTAMATE RECEPTORS | ASTRAZENECA AB (SE) | 2004-02-19 | — | — | WO | claimed |
| EP-1065206-B1 | Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents | PFIZER (US) | 2002-10-09 | — | — | EP | claimed |
| US-20260091027-A1 | STILBENE DERIVATIVES AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | THEDERMA SHANGHAI CO LTD (CN) | 2026-04-02 | — | — | US | disclosed |
| US-12582645-B2 | Chemokine CXCR4 receptor modulators and uses related thereto | EMORY UNIVERSITY (US) | 2026-03-24 | — | — | US | disclosed |
| EP-4126835-B1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2026-02-18 | — | — | EP | disclosed |
| US-12516038-B2 | Inhibitors of antigen presentation by HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2026-01-06 | — | — | US | disclosed |
| EP-1214322-A2 | AMINO-TRIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-06-19 | — | — | EP | disclosed |
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |
| WO-2001017999-A2 | AMINO-TRIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-03-15 | — | — | WO | disclosed |
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |