Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26698651 | 0.82 | MTNR1A (0.45) | MTNR1AMTNR1B | |
| SCHEMBL26931313 | 0.80 | TXNRD1 (0.52) | NPC1RAB9A | |
| SCHEMBL26611752 | 0.75 | SMN1; SMN2 (0.39) | MTNR1AMTNR1BNPC1RAB9ACA12 | |
| SCHEMBL26612125 | 0.74 | NNMT (0.40) | POLBTDP1 | |
| SCHEMBL26611992 | 0.74 | SMN1; SMN2 (0.44) | MTNR1AMTNR1BNPC1RAB9APOLB | |
| SCHEMBL8785416 | 0.73 | PDE4B (0.41) | POLBTDP1 | |
| SCHEMBL26611719 | 0.73 | MTNR1A (0.39) | MTNR1AMTNR1BRAB9ACA1CA2 | |
| SCHEMBL26611757 | 0.73 | SMN1; SMN2 (0.43) | MTNR1AMTNR1BPOLB | |
| SCHEMBL20562599 | 0.73 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL27447499 | 0.73 | KDM4E (0.46) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205116-A1 | PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |