SCHEMBL266234

SCHEMBL266234

c1ccc(C2=NN(c3ccccc3)CN(c3ccccc3)[N]2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 6/20 0.46
▸ RAB9A P51151 6/20 0.46
▸ MAPT P10636 4/20 0.46
▸ KDM4E B2RXH2 3/20 0.46
▸ MAPK1 P28482 3/20 0.46
▸ TDP1 Q9NUW8 2/20 0.46
▸ GLA P06280 2/20 0.46
▸ L3MBTL1 Q9Y468 2/20 0.46
▸ MAOB P27338 2/20 0.37
▸ ALDH1A1 P00352 3/20 0.34
▸ HPGD P15428 1/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ MCL1 Q07820 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ PTGS2 P35354 3/20 0.33
▸ PTGS1 P23219 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ ALB P02768 2/20 0.33
▸ LMNA P02545 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL267477 0.79 CYP1A2 (0.45) NPC1RAB9AMAPTKDM4EMAPK1
SCHEMBL14107198 0.72 NPC1 (0.44) NPC1RAB9AMAPTKDM4EMAPK1
SCHEMBL852946 0.71 NPC1 (0.47) NPC1RAB9AMAPTKDM4EMAPK1
Iodide SCHEMBL11899495 0.69 NPC1 (0.46) NPC1RAB9AMAPTKDM4EMAPK1
SCHEMBL14081302 0.68 MAPT (0.41) NPC1RAB9AMAPTKDM4EMAPK1
SCHEMBL15031208 0.66 MAPT (0.42) NPC1RAB9AMAPTKDM4EMAPK1
SCHEMBL265449 0.66 L3MBTL1 (0.42) NPC1RAB9AMAPTKDM4EMAPK1
SCHEMBL14575860 0.65 NPC1 (0.41) NPC1RAB9AMAPTKDM4EMAPK1
SCHEMBL157594 0.63 MAPT (1.00) NPC1RAB9AMAPTKDM4EMAPK1
SCHEMBL1684314 0.61 L3MBTL1 (0.46) NPC1RAB9AMAPTKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230098037-A1 POLYMER COMPOSITION, MOLDED ARTICLE, AND OPTICAL MEMBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-03-30 — — US claimed
EP-4098673-A1 POLYMER COMPOSITION, MOLDED BODY, AND OPTICAL MEMBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-12-07 — — EP claimed
EP-1655070-B1 OXIDATION CATALYST ASAHI KASEI CHEMICALS CORP (JP) 2015-07-15 — — EP claimed
US-8133834-B2 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-03-13 — — US claimed
US-20100069670-A1 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-03-18 — — US claimed
US-20060229471-A1 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2006-10-12 — — US claimed
EP-1655070-A1 OXIDATION CATALYST Asahi Kasei Chemicals Corporation (JP) 2006-05-10 — — EP claimed
CN-115003751-B Polymer composition, molded body, and optical member 住友化学株式会社 2024-07-09 — — CN disclosed
CN-111837075-B Negative super thick film photoresist 默克专利股份有限公司 2024-07-05 — — CN disclosed
EP-3769156-B1 NEGATIVE-WORKING ULTRA THICK FILM PHOTORESIST MERCK PATENT GMBH (DE) 2024-03-20 — — EP disclosed
US-11698586-B2 Negative-working ultra thick film photoresist MERCK PATENT GMBH (DE) 2023-07-11 — — US disclosed
US-20230098037-A1 POLYMER COMPOSITION, MOLDED ARTICLE, AND OPTICAL MEMBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-03-30 — — US disclosed
US-20230098037-A1 POLYMER COMPOSITION, MOLDED ARTICLE, AND OPTICAL MEMBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-03-30 — — US disclosed
EP-4098673-A1 POLYMER COMPOSITION, MOLDED BODY, AND OPTICAL MEMBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-12-07 — — EP disclosed
EP-4098673-A1 POLYMER COMPOSITION, MOLDED BODY, AND OPTICAL MEMBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-12-07 — — EP disclosed
EP-1655070-B1 OXIDATION CATALYST ASAHI KASEI CHEMICALS CORP (JP) 2015-07-15 — — EP disclosed
US-8133834-B2 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-03-13 — — US disclosed
US-20100069670-A1 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-03-18 — — US disclosed
US-20060229471-A1 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2006-10-12 — — US disclosed
EP-1655070-A1 OXIDATION CATALYST Asahi Kasei Chemicals Corporation (JP) 2006-05-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069670-A1 Oxidation catalyst PPOX, SOD1, HAO2 NPC1 4725/4885RAB9A 4804/4885MAPT 3864/4885
US-20060229471-A1 Oxidation catalyst PPOX, SOD1, HAO2 NPC1 4725/4885RAB9A 4804/4885MAPT 3864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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