SCHEMBL26623992

SCHEMBL26623992

O=C(c1c(F)c(F)c(F)c(F)c1F)n1nnc2ccccc21

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MGAM O43451 10/20 0.75
▸ AMY1A P0DUB6 10/20 0.75
▸ GAA P10253 10/20 0.75
▸ SI P14410 10/20 0.75
▸ MGAM2 Q2M2H8 10/20 0.75
▸ KMT2A Q03164 4/20 0.64
▸ HPGD P15428 2/20 0.64
▸ F2 P00734 1/20 0.64
▸ SLC9A1 P19634 1/20 0.64
▸ KCNMA1 Q12791 1/20 0.59
▸ F12 P00748 6/20 0.57
▸ MAPT P10636 3/20 0.55
▸ ALDH1A1 P00352 2/20 0.55
▸ KDM4E B2RXH2 1/20 0.55
▸ HTT P42858 1/20 0.55
▸ NPSR1 Q6W5P4 1/20 0.55
▸ MIF P14174 1/20 0.54
▸ HSD17B10 Q99714 2/20 0.53
▸ DGAT1 O75907 1/20 0.53
▸ GLA P06280 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3900498 0.80 KCNMA1 (0.81) MGAMAMY1AGAASIMGAM2
SCHEMBL2493323 0.79 MGAM (1.00) MGAMAMY1AGAASIMGAM2
SCHEMBL29433322 0.78 MGAM (1.00) MGAMAMY1AGAASIMGAM2
SCHEMBL2493561 0.78 MGAM (1.00) MGAMAMY1AGAASIMGAM2
SCHEMBL10621117 0.78 GAA (0.64) MGAMAMY1AGAASIMGAM2
SCHEMBL23060410 0.77 MGAM (0.54) MGAMAMY1AGAASIMGAM2
SCHEMBL706083 0.77 MGAM (0.68) MGAMAMY1AGAASIMGAM2
SCHEMBL4250719 0.77 GAA (0.68) MGAMAMY1AGAASIMGAM2
SCHEMBL170673 0.75 GAA (0.71) MGAMAMY1AGAASIMGAM2
SCHEMBL1756653 0.75 DGAT1 (0.69) MGAMAMY1AGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337677-A1 ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2023-10-26 — — US disclosed
US-20230337677-A1 ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2023-10-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337677-A1 ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF DDT, ACHE, AHR MGAM 4555/4885AMY1A 3371/4885GAA 4686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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