SCHEMBL26624153

SCHEMBL26624153

C=CCOC[C@H]1[C@@H](O)[C@H](n2cnc3c(=O)[nH]c(N)nc32)O[C@@H]1COP(=O)(O)OP(=O)(O)O

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.66
KRAS P01116 5/20 0.63
NT5E P21589 1/20 0.59
FUT5 Q11128 1/20 0.58
IMPDH2 P12268 4/20 0.56
P2RY6 Q15077 2/20 0.55
P2RY2 P41231 1/20 0.55
P2RY4 P51582 1/20 0.55
DCPS Q96C86 1/20 0.53
P2RX3 P56373 2/20 0.53
IMPDH1 P20839 2/20 0.53
POLB P06746 1/20 0.52
ENPP1 P22413 2/20 0.52
P2RY1 P47900 2/20 0.52
P2RY12 Q9H244 1/20 0.52
P2RX1 P51575 1/20 0.51
P2RY11 Q96G91 1/20 0.51
P2RX4 Q99571 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26209516 1.00 TGM2 (0.66) TGM2KRASNT5EFUT5IMPDH2
SCHEMBL26209514 0.94 IMPDH2 (0.63) TGM2KRASNT5EFUT5IMPDH2
SCHEMBL26622655 0.90 TGM2 (0.66) TGM2KRASNT5EFUT5IMPDH2
SCHEMBL26622787 0.90 TGM2 (0.70) TGM2KRASNT5EFUT5IMPDH2
SCHEMBL17198633 0.89 TGM2 (0.69) TGM2KRASNT5EFUT5IMPDH2
SCHEMBL26207486 0.89 TGM2 (0.65) TGM2KRASNT5EFUT5IMPDH2
SCHEMBL26622717 0.89 TGM2 (0.65) TGM2KRASNT5EFUT5IMPDH2
SCHEMBL26622665 0.88 TGM2 (0.68) TGM2KRASNT5EFUT5IMPDH2
SCHEMBL17198455 0.87 TGM2 (0.69) TGM2KRASNT5EFUT5IMPDH2
SCHEMBL17198180 0.87 TGM2 (0.69) TGM2KRASNT5EFUT5IMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 US disclosed
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF RNGTT, RNMT, NSUN2 TGM2 2548/4885KRAS 2017/4885NT5E 803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.